Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.62 |
| ▸ | CES1 | P23141 | 5/20 | 0.62 |
| ▸ | CES2 | O00748 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARD | Q03181 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tridecane SCHEMBL27500702 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Decane SCHEMBL3416451 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL28781369 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Dodecane SCHEMBL30416006 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Undecane SCHEMBL3628539 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Nonane SCHEMBL4255344 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Heptane SCHEMBL3935940 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Hexadecane SCHEMBL4765353 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Octane SCHEMBL1696265 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| Heptane SCHEMBL28333176 | 1.00 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016775-A1 | ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR | FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD (CN) | 2024-01-18 | — | — | US | claimed |
| EP-4112049-A1 | ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR | Fukang (Shanghai) Health Technology Co., Ltd. (CN) | 2023-01-04 | — | — | EP | claimed |
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | claimed |
| CN-102947300-B | Alkaloid amino ester derivative and pharmaceutical composition thereof | 奇斯药制品公司 | 2016-09-21 | — | — | CN | claimed |
| CN-102264734-B | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMA SPA | 2015-06-17 | — | — | CN | claimed |
| CN-102264734-A | Alkaloid aminoester derivatives and medicinal composition thereof | — | 2011-11-30 | — | — | CN | claimed |
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | claimed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | claimed |
| EP-1711183-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-04-01 | — | — | EP | claimed |
| CN-100404533-C | New quinuclidine amide derivatives | ALMIRALL PRODESFARMA AG (CH) | 2008-07-23 | — | — | CN | claimed |
| CN-100363363-C | Quinuclidine derivatives and pharmaceutical compositions containing the same | ALMIRALL PRODESFARMA SA (CH) | 2008-01-23 | — | — | CN | claimed |
| CN-1930158-A | New quaternized quinuclidine esters | ALMIRALL PRODESFARMA SA (ES) | 2007-03-14 | — | — | CN | claimed |
| EP-1711183-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-10-18 | — | — | EP | claimed |
| CN-1250545-C | Novel quinuclidine derivatives and pharmaceutical compositions containing them | ALMIRALL PRODESFARMA AG (CH) | 2006-04-12 | — | — | CN | claimed |
| CN-1678610-A | New quinuclidine amide derivatives | ALMIRALL PRODESFARMA AG (CH) | 2005-10-05 | — | — | CN | claimed |
| CN-1675206-A | Quinuclidine derivatives and pharmaceutical compositions containing the same | ALMIRALL PRODESFARMA SA (CH) | 2005-09-28 | — | — | CN | claimed |
| WO-2005067537-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-28 | — | — | WO | claimed |
| CN-1487938-A | Quinuclidine derivatives and their use as M3 antagonists | ������ҩ������˾ | 2004-04-07 | — | — | CN | claimed |
| CN-113288892-B | Use of poly ADP-ribose polymerase inhibitors against coronaviruses | 甫康（上海）健康科技有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-111868055-B | Inhibitors of TRPC6 | 勃林格殷格翰国际有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20240016775-A1 | ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR | FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD (CN) | 2024-01-18 | — | — | US | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114621190-B | Allylamine derivative and application thereof | 上海拓界生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-114591334-B | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-3883936-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2023-07-12 | — | — | EP | disclosed |
| EP-4112049-A1 | ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR | Fukang (Shanghai) Health Technology Co., Ltd. (CN) | 2023-01-04 | — | — | EP | disclosed |
| CN-114621190-A | Allylamine derivative and application thereof | 上海拓界生物医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114591334-A | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555592-A | 2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114364682-A | Compound 4,4A,5,7,8, 8A-hexapyrido [4,3-B ] [1,4] oxazin-3-one as MAGL inhibitor | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-3883936-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2021-09-29 | — | — | EP | disclosed |
| CN-113329748-A | Inhibition of Fatty Acid Synthase (FASN) | 福马治疗股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-113166108-A | Fused pyrrolines as inhibitors of ubiquitin-specific protease 30(USP30) | 福马治疗有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113166170-A | Novel heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-3807269-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | F. Hoffmann-La Roche AG (CH) | 2021-04-21 | — | — | EP | disclosed |
| EP-3788043-A1 | SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | Merck Sharp & Dohme Corp. (US) | 2021-03-10 | — | — | EP | disclosed |
| CN-112424196-A | Novel isoxazolyl ether derivatives as GABAA alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112119076-A | Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors | 默沙东公司 | 2020-12-22 | — | — | CN | disclosed |
| WO-2019238633-A1 | NEW ISOXAZOLYL ETHER DERIVATIVES AS GABA A ALPHA5 PAM | F. HOFFMANN-LA ROCHE AG (CH) | 2019-12-19 | — | — | WO | disclosed |
| CN-110446700-A | Compound | GLAXOSMITHKLINE IP DEV LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-102838605-B | Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloalkanes | 塔加西普特公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-102947300-B | Alkaloid amino ester derivative and pharmaceutical composition thereof | 奇斯药制品公司 | 2016-09-21 | — | — | CN | disclosed |
| EP-2643295-B1 | GLYCINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARMA SPA (IT) | 2016-04-13 | — | — | EP | disclosed |
| CN-103635456-B | Tigecycline derivatives | KBP BIOSCIENCES Co.,Ltd. (CN) | 2016-03-09 | — | — | CN | disclosed |
| CN-102947298-B | Alkaloid aminoester derivatives and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-03-02 | — | — | CN | disclosed |
| CN-103717571-B | The tetracycline compound that 9-amino methyl replaces | KBP BIOSCIENCES Co.,Ltd. (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-102942569-B | The acid amides of alkalescence acetylcholine receptor subtypes optionally diazabicylo alkane | TARGACEPT INC. (US) | 2015-10-28 | — | — | CN | disclosed |
| CN-102417480-B | As the Spirocyclic nitriles of proteinase inhibitor | Sanofi-Aventis S. P. A. (FR) | 2015-08-26 | — | — | CN | disclosed |
| CN-102516241-B | The azabicyclic alkane derivatives of the bicyclic heterocycle the condensed replacement of CNS activity | Abbott Labaoratories (BS) | 2015-07-29 | — | — | CN | disclosed |
| CN-102947299-B | Alkaloid aminoester derivatives and pharmaceutical compositions thereof | CHIESI FARMA SPA | 2015-07-15 | — | — | CN | disclosed |
| CN-102264734-B | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMA SPA | 2015-06-17 | — | — | CN | disclosed |
| CN-103221390-B | Glycine derivatives and pharmaceutical compositions thereof | CHIESI FARMA SPA | 2015-06-03 | — | — | CN | disclosed |
| EP-2797910-A1 | QUINUCLIDINE ESTERS OF 1-AZAHETEROCYCLYLACETIC ACID AS ANTIMUSCARINIC AGENTS, PROCESS FOR THEIR PREPARATION AND MEDICINAL COMPOSITIONS THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2014-11-05 | — | — | EP | disclosed |
| EP-2780026-A2 | HCV NS3 PROTEASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2014-09-24 | — | — | EP | disclosed |
| CN-104011043-A | Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof | CHIESI FARMA SPA | 2014-08-27 | — | — | CN | disclosed |
| CN-102459232-B | 7-aza-spiro[3.5]nonane-7-carboxylate derivatives, preparation thereof, and therapeutic use thereof | SANOFI AVENTIS | 2014-05-07 | — | — | CN | disclosed |
| EP-2702041-A1 | ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2014-03-05 | — | — | EP | disclosed |
| CN-103502213-A | Alkaloid ester and carbamate derivatives and medicinal compositions thereof | CHIESI FARMA SPA | 2014-01-08 | — | — | CN | disclosed |
| CN-102020646-B | Nicotinic acetylcholine receptorsub-type selective amides of diazabicycloalkanes | TARGACEPT INC | 2013-11-13 | — | — | CN | disclosed |
| EP-2643295-A1 | GLYCINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | Chiesi Farmaceutici S.p.A. (IT) | 2013-10-02 | — | — | EP | disclosed |
| CN-101460462-B | Spirocyclic nitriles as protease inhibitors | SANOFI AVENTIS SPA | 2013-07-31 | — | — | CN | disclosed |
| CN-103221390-A | Glycine derivatives and pharmaceutical compositions thereof | CHIESI FARMA SPA | 2013-07-24 | — | — | CN | disclosed |
| CN-101367794-B | Preparation method for quinazoline derivants and medical uses thereof | SHANGHAI HENGRUI PHARM CO LTD | 2013-07-10 | — | — | CN | disclosed |
| WO-2013098145-A1 | QUINUCLIDINE ESTERS OF 1-AZAHETEROCYCLYLACETIC ACID AS ANTIMUSCARINIC AGENTS, PROCESS FOR THEIR PREPARATION AND MEDICINAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013074386-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |
| EP-2585457-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2013-05-01 | — | — | EP | disclosed |
| EP-2585459-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2013-05-01 | — | — | EP | disclosed |
| EP-2585458-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2013-05-01 | — | — | EP | disclosed |
| CN-101415686-B | Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO | 2013-03-13 | — | — | CN | disclosed |
| CN-102947298-A | Alkaloid aminoester derivatives and pharmaceutical compositions thereof | CHIESI FARMA SPA | 2013-02-27 | — | — | CN | disclosed |
| CN-102947300-A | Alkaloid aminoester derivatives and medicinal compositions thereof | CHIESI FARMA SPA | 2013-02-27 | — | — | CN | disclosed |
| CN-102942569-A | Nicotinic acetylcholine receptorsub-type selective amides of diazabicycloalkanes | TARGACEPT INC | 2013-02-27 | — | — | CN | disclosed |
| CN-102947299-A | Alkaloid aminoester derivatives and pharmaceutical compositions thereof | CHIESI FARMA SPA | 2013-02-27 | — | — | CN | disclosed |
| CN-102838605-A | Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloalkanes | TARGACEPT INC | 2012-12-26 | — | — | CN | disclosed |
| WO-2012146515-A1 | ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-11-01 | — | — | WO | disclosed |
| CN-102516241-A | CNS active fused bicycloheterocycle substituted azabicyclic alkane derivatives | ABBOTT LAB | 2012-06-27 | — | — | CN | disclosed |
| WO-2012069275-A1 | GLYCINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-05-31 | — | — | WO | disclosed |
| CN-102459232-A | 7-aza-spiro [3.5] nonane-7-carboxylate derivatives, preparation thereof and therapeutic use thereof | SANOFI AVENTIS | 2012-05-16 | — | — | CN | disclosed |
| CN-102417480-A | Spirocyclic nitriles as protease inhibitors | SANOFI AVENTIS | 2012-04-18 | — | — | CN | disclosed |
| WO-2011160918-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011160919-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011161018-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | WO | disclosed |
| CN-102264734-A | Alkaloid aminoester derivatives and medicinal composition thereof | — | 2011-11-30 | — | — | CN | disclosed |
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | disclosed |
| CN-102216289-A | Nicotinic acetylcholine receptor ligands and uses thereof | PSYCHOGENICS INC | 2011-10-12 | — | — | CN | disclosed |
| CN-101528745-B | Amides of basic acetylcholine receptor subtype selective diazadicycloalkanes | TARGACEPT INC | 2011-09-14 | — | — | CN | disclosed |
| CN-101119968-B | Heterocyclically substituted phenyl methanone derivatives as glycine transporter 1 inhibitors | HOFFMANN LA ROCHE | 2011-08-31 | — | — | CN | disclosed |
| EP-1806339-B1 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB PHARMA SA (BE) | 2011-08-17 | — | — | EP | disclosed |
| CN-101115742-B | Heterocycle derivatives as histone deacetylase (hdac) inhibitors | ANGELETTI P IST RICHERCHE BIO | 2011-06-22 | — | — | CN | disclosed |
| EP-2094703-B1 | NICOTINIC ACETYLCHOLINE RECEPTORSUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOALKANES | TARGACEPT INC (US) | 2011-05-11 | — | — | EP | disclosed |
| CN-102020646-A | Nicotinic acetylcholine receptorsub-type selective amides of diazabicycloalkanes | TARGACEPT INC | 2011-04-20 | — | — | CN | disclosed |
| EP-2284171-A1 | Amides of diazabicycloalkanes selective for nicotinic acetylcholine receptor sub-types | Targacept, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | disclosed |
| CN-101018786-B | Process for preparing quinuclidinium carbamate derivatives | ALMIRALL LAB | 2010-05-05 | — | — | CN | disclosed |
| CN-100569771-C | As 5-HT4Quinolinone-carboxamide compounds as receptor agonists | THERAVANCE INC (US) | 2009-12-16 | — | — | CN | disclosed |
| CN-101528745-A | Amides of basic acetylcholine receptor subtype selective diazadicycloalkanes | TARGACEPT INC (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-1765339-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-2094703-A1 | NICOTINIC ACETYLCHOLINE RECEPTORSUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOALKANES | Targacept, Inc. (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-1631569-B1 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | NOVARTIS AG (CH) | 2009-08-26 | — | — | EP | disclosed |
| CN-101460462-A | Spirocyclic nitriles as protease inhibitors | SANOFI AVENTIS (FR) | 2009-06-17 | — | — | CN | disclosed |
| CN-101448825-A | CNS active fused bicyclic heterocycle substituted azabicycloalkane derivatives | ABBOTT LAB (US) | 2009-06-03 | — | — | CN | disclosed |
| CN-101415686-A | Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-04-22 | — | — | CN | disclosed |
| EP-1711183-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-04-01 | — | — | EP | disclosed |
| EP-2032140-A1 | PYRROLO[1,2-A]PYRAZIN-1(2H)-ONE AND PYRROLO[1,2-D][1,2,4]TRIAZIN-1(2H)-ONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE(PARP) | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2009-03-11 | — | — | EP | disclosed |
| CN-101367794-A | Preparation method for quinazoline derivants and medical uses thereof | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2009-02-18 | — | — | CN | disclosed |
| CN-100445281-C | Quinuclidine derivatives binding to muscarinic M3 receptor | NOVARTIS AG (CH) | 2008-12-24 | — | — | CN | disclosed |
| CN-101238121-A | Fused bicyclic heterocycle substituted quinuclidine derivatives | ABBOTT LAB (US) | 2008-08-06 | — | — | CN | disclosed |
| CN-100404533-C | New quinuclidine amide derivatives | ALMIRALL PRODESFARMA AG (CH) | 2008-07-23 | — | — | CN | disclosed |
| WO-2008057938-A1 | NICOTINIC ACETYLCHOLINE RECEPTORSUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOALKANES | TARGACEPT, INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| CN-101119968-A | Heterocyclically substituted phenyl methanone derivatives as glycine transporter 1 inhibitors | HOFFMANN LA ROCHE (CH) | 2008-02-06 | — | — | CN | disclosed |
| CN-101115742-A | Heterocycle derivatives as histone deacetylase (hdac) inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2008-01-30 | — | — | CN | disclosed |
| CN-100363363-C | Quinuclidine derivatives and pharmaceutical compositions containing the same | ALMIRALL PRODESFARMA SA (CH) | 2008-01-23 | — | — | CN | disclosed |
| WO-2007138355-A1 | PYRROLO[1,2-A]PYRAZIN-1(2H)-ONE AND PYRROLO[1,2-D][1,2,4]TRIAZIN-1(2H)-ONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE(PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-12-06 | — | — | WO | disclosed |
| CN-101018786-A | Process for preparing quinuclidinium carbamate derivatives | ALMIRALL LAB (ES) | 2007-08-15 | — | — | CN | disclosed |
| CN-1946719-A | As 5-HT4Quinolinone-carboxamide compounds as receptor agonists | THERAVANCE INC (US) | 2007-04-11 | — | — | CN | disclosed |
| EP-1765339-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-03-28 | — | — | EP | disclosed |
| US-20070060563-A1 | Quinuclidine derivatives binding to mucarinic m3 receptors | NOVARTIS AG (CH) | 2007-03-15 | — | — | US | disclosed |
| CN-1930158-A | New quaternized quinuclidine esters | ALMIRALL PRODESFARMA SA (ES) | 2007-03-14 | — | — | CN | disclosed |
| EP-1711183-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-10-18 | — | — | EP | disclosed |
| CN-1784400-A | Quinuclidine derivatives binding to muscarinic M3 receptor | NOVARTIS AG (CH) | 2006-06-07 | — | — | CN | disclosed |
| CN-1250545-C | Novel quinuclidine derivatives and pharmaceutical compositions containing them | ALMIRALL PRODESFARMA AG (CH) | 2006-04-12 | — | — | CN | disclosed |
| WO-2006005057-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |
| CN-1678610-A | New quinuclidine amide derivatives | ALMIRALL PRODESFARMA AG (CH) | 2005-10-05 | — | — | CN | disclosed |
| CN-1675206-A | Quinuclidine derivatives and pharmaceutical compositions containing the same | ALMIRALL PRODESFARMA SA (CH) | 2005-09-28 | — | — | CN | disclosed |
| CN-1662493-A | Ring-substituted diphenyl 2-azetidinones, method for the production thereof, medicaments containing said compounds and the use thereof | AVENTIS PHARMA GMBH (DE) | 2005-08-31 | — | — | CN | disclosed |
| CN-1662494-A | Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use | AVENTIS PHARMA GMBH (DE) | 2005-08-31 | — | — | CN | disclosed |
| WO-2005067537-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-28 | — | — | WO | disclosed |
| CN-1487938-A | Quinuclidine derivatives and their use as M3 antagonists | ������ҩ������˾ | 2004-04-07 | — | — | CN | disclosed |
| CN-1487938-A | Quinuclidine derivatives and their use as M3 antagonists | ������ҩ������˾ | 2004-04-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060563-A1 | Quinuclidine derivatives binding to mucarinic m3 receptors | CHRM3, CHRM2, CHRM1 | FAAH 3333/4885CES1 2111/4885CES2 1608/4885 |
| US-20240016775-A1 | ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR | PARP3, PARP1, PARP4 | FAAH 2648/4885CES1 3226/4885CES2 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.