Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238363 | 0.88 | NPC1 (0.54) | MAPTSIRT2MEN1KMT2ASMN1; SMN2 | |
| Diflubenzuron SCHEMBL18837607 | 0.85 | RAB9A (0.59) | MAPTMEN1KMT2ARAB9ANPC1 | |
| Diflubenzuron SCHEMBL42416 | 0.85 | RAB9A (0.59) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9324631 | 0.83 | RAB9A (0.57) | MAPTMEN1KMT2ARAB9ANPC1 | |
| Diflubenzuron SCHEMBL8729691 | 0.81 | NPC1 (0.56) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10711203 | 0.81 | RAB9A (0.56) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11242722 | 0.81 | GCGR (0.54) | MAPTSIRT2MEN1KMT2ASMN1; SMN2 | |
| Diflubenzuron SCHEMBL28169066 | 0.80 | NPC1 (0.54) | MEN1KMT2ARAB9ANPC1PKM | |
| SCHEMBL11381816 | 0.80 | NPC1 (0.50) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11246141 | 0.79 | ATM (0.46) | MAPTMEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |