SCHEMBL1123665

SCHEMBL1123665

C=CC(=O)N1C(=O)CCC1=O

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 15/20 0.49
KCNH2 Q12809 1/20 0.34
ACHE P22303 3/20 0.33
PAX8 Q06710 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL27874468 0.91 GSK3B (0.44) GSK3BKCNH2ACHE
SCHEMBL27614295 0.91 GSK3B (0.44) GSK3BKCNH2ACHEPAX8
SCHEMBL11602274 0.85 GSK3B (0.43) GSK3BKCNH2
SCHEMBL2359222 0.77 GSK3B (0.35) GSK3B
SCHEMBL10314831 0.77 GSK3B (0.32) GSK3B
SCHEMBL28507221 0.75 GSK3B (0.31) GSK3B
SCHEMBL12764295 0.71
SCHEMBL7157486 0.70 GSK3B (0.43) GSK3BKCNH2
SCHEMBL2267710 0.70 GSK3B (0.38) GSK3BKCNH2ACHEPAX8
SCHEMBL23733173 0.69 CA12 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025123597-A1 PROTEIN CARRIER-BASED ACTIVE INGREDIENT TRANSDERMAL DELIVERY SYSTEM, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海交通大学 2025-06-19 WO claimed
US-11572429-B2 Hydrogels based on vinyl-caprolactam CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) 2023-02-07 US claimed
WO-2019193236-A1 HYDROGELS BASED ON VINYL CAPROLACTAM CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2019-10-10 WO claimed
CN-101791541-B Preparation method of chromatographic particle medium BEIJING JIUQIANG BIOTECHNOLOGY CO LTD 2013-06-05 CN claimed
CN-101791543-B Preparation method of chromatographic particle medium BEIJING STRONG BIOTECHNOLOGIES INC 2013-04-10 CN claimed
CN-101791541-A Preparation method of chromatographic particle medium BEIJING STRONG BIOTECHNOLOGIES INC 2010-08-04 CN claimed
CN-1689695-B Preparation method of chromatographic particle medium BEIJING STRONG BIOTECHNOLOGIES INC 2010-06-23 CN claimed
US-7674382-B2 Method of cleaning fouled and/or scaled membranes NALCO COMPANY (US) 2010-03-09 US claimed
US-7662289-B2 Method of cleaning fouled or scaled membranes NALCO COMPANY (US) 2010-02-16 US claimed
WO-2008137663-A1 METHOD OF CLEANING FOULED AND/OR SCALED MEMBRANES NALCO COMPANY (US) 2008-11-13 WO claimed
US-7355020-B2 Stimulus responsive affinity chromatographic material and separation/purification method GE HEALTHCARE BIO-SCIENCES KK (JP) 2008-04-08 US claimed
WO-2006128644-A1 POLYMER COATING AND FUNCTIONALIZATION OF SOLID SURFACES PIRRI GIOVANNA (IT) 2006-12-07 WO claimed
US-20060060516-A1 Stimulus responsive affinity chromatographic material and separation/purification method Okano, Teruo 2006-03-23 US claimed
US-7012136-B2 Stimulus responsive affinity chromatographic material and separation/purification method AMERSHAM BIOSCIENCES KK (JP) 2006-03-14 US claimed
CN-1689695-A Preparation method of chromatographic particle medium BEIJING GAORUNTONG BIO TECHNOL (CN) 2005-11-02 CN claimed
US-20040039177-A1 Stimulus responsive affinity chromatographic material and separation/purification method GE HEALTHCARE BIO-SCIENCES KK (JP) 2004-02-26 US claimed
EP-1347831-A1 STIMULUS RESPONSIVE AFFINITY CHROMATOGRAPHIC MATERIAL AND SEPARATION/PURIFICATION METHOD Amersham Biosciences KK (JP) 2003-10-01 EP claimed
WO-2002030564-A1 STIMULUS RESPONSIVE AFFINITY CHROMATOGRAPHIC MATERIAL AND SEPARATION/PURIFICATION METHOD AMERSHAM BIOSCIENCES K.K. (JP) 2002-04-18 WO claimed
US-4228152-A BOUND TO A POLYACRYLIC OR POLYMETHACRYLIC BACKBONE THROUGH ESTER OR AMIDIC BONDS FERRUTI PAOLO 1980-10-14 US claimed
US-4067876-A SUSTAINED RELEASE FERRUTI PAOLO 1978-01-10 US claimed