SCHEMBL7157486

SCHEMBL7157486

C=CC(=O)N1C(=O)CC(O)C1=O

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 18/20 0.43
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1635519 0.75 MAPT (0.31)
SCHEMBL31530628 0.75 GSK3B (0.40) GSK3BKCNH2
SCHEMBL14391569 0.74 NOTUM (0.35)
SCHEMBL3944013 0.73
SCHEMBL1123665 0.70 GSK3B (0.49) GSK3BKCNH2
SCHEMBL8815627 0.69
SCHEMBL5670121 0.69
SCHEMBL6032187 0.66
SCHEMBL7077014 0.65 ALDH1A1 (0.40)
SCHEMBL27614295 0.64 GSK3B (0.44) GSK3BKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6538089-B1 Crosslinked terpolymer comprising monomers of N-isopropylacrylamide, N-acryloyloxysuccinimide, and styrene; drug delivery FORSKARPATENT I SYD AB (SE) 2003-03-25 US claimed
WO-2000046262-A1 GELS WITH A SHAPE MEMORY FORSKARPATENT I SYD AB (SE) 2000-08-10 WO claimed
US-6538089-B1 Crosslinked terpolymer comprising monomers of N-isopropylacrylamide, N-acryloyloxysuccinimide, and styrene; drug delivery FORSKARPATENT I SYD AB (SE) 2003-03-25 US disclosed
WO-2000046262-A1 GELS WITH A SHAPE MEMORY FORSKARPATENT I SYD AB (SE) 2000-08-10 WO disclosed