Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11141993 | 0.99 | SMN1; SMN2 (0.39) | SMN1; SMN2GLAMEN1KMT2APOLB | |
| SCHEMBL11222122 | 0.97 | SMN1; SMN2 (0.40) | SMN1; SMN2GLAMEN1KMT2APOLB | |
| SCHEMBL11236572 | 0.96 | GLA (0.40) | SMN1; SMN2GLAMEN1KMT2APOLB | |
| Bromide SCHEMBL11147068 | 0.95 | GLA (0.39) | SMN1; SMN2GLAMEN1KMT2APOLB | |
| SCHEMBL11227955 | 0.76 | EGFR (0.33) | — | |
| SCHEMBL11236299 | 0.74 | CACNA1B (0.33) | — | |
| SCHEMBL11227711 | 0.74 | MAOB (0.39) | SMN1; SMN2L3MBTL1MAPT | |
| Bromide SCHEMBL11137501 | 0.73 | CACNA1B (0.32) | — | |
| SCHEMBL11142208 | 0.73 | CA4 (0.32) | — | |
| SCHEMBL11245133 | 0.71 | CA4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336252-A | 1-Cycloalkyl phosphonium salts | G. D. SEARLE & CO. (US) | 1982-06-22 | — | — | US | claimed |