Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.31 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.31 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.31 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.31 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.31 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.31 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.31 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.31 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11137501 | 0.99 | CACNA1B (0.32) | CACNA1BADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11225526 | 0.97 | NDUFS8 (0.33) | CACNA1BADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11232289 | 0.96 | NDUFS8 (0.33) | CACNA1BADRA2AADRA2BADRA2CADRA1D | |
| Bromide SCHEMBL11240464 | 0.95 | NDUFS8 (0.32) | CACNA1BADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11227711 | 0.75 | MAOB (0.39) | MAOB | |
| SCHEMBL11237005 | 0.74 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL11227955 | 0.74 | EGFR (0.33) | — | |
| Bromide SCHEMBL11141993 | 0.73 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL11236301 | 0.72 | KDM1A (0.30) | — | |
| SCHEMBL11233344 | 0.72 | MAOB (0.39) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336252-A | 1-Cycloalkyl phosphonium salts | G. D. SEARLE & CO. (US) | 1982-06-22 | — | — | US | claimed |