Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227373 | 0.87 | GRIN1 (0.57) | GRIN1GRIN2B | |
| SCHEMBL11230943 | 0.85 | GRIN1 (0.55) | GRIN1GRIN2B | |
| SCHEMBL11235759 | 0.85 | GRIN1 (0.41) | GRIN1GRIN2B | |
| SCHEMBL11236623 | 0.84 | GRIN1 (0.55) | GRIN1GRIN2B | |
| SCHEMBL11233554 | 0.84 | GRIN1 (0.53) | GRIN1GRIN2B | |
| SCHEMBL11244916 | 0.83 | GRIN1 (0.61) | GRIN1GRIN2B | |
| SCHEMBL11240463 | 0.82 | GRIN1 (0.57) | GRIN1GRIN2B | |
| SCHEMBL11243184 | 0.82 | GRIN1 (0.52) | GRIN1GRIN2B | |
| SCHEMBL11237188 | 0.81 | GRIN1 (0.67) | GRIN1GRIN2B | |
| SCHEMBL11233739 | 0.80 | GRIN1 (0.49) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309537-A | Production of imidazo[4,5-b]pyridin-2-ones or thiones | STERLING DRUG INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4297360-A | 5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use | STERLING DRUG INC. (US) | 1981-10-27 | — | — | US | disclosed |
| US-4294837-A | 1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use | STERLING DRUG INC. (US) | 1981-10-13 | — | — | US | disclosed |