Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083435 | 0.88 | TDP1 (0.40) | HTTTSHRMAPTTDP1PPARA | |
| SCHEMBL11042836 | 0.87 | LTB4R (0.40) | HTTTP53TSHRPLA2G4BTDP1 | |
| SCHEMBL11048926 | 0.87 | LTB4R (0.40) | HTTTP53TSHRPLA2G4BTDP1 | |
| SCHEMBL18813866 | 0.82 | SERPINE1 (0.40) | HTTMAPTTDP1POLBMAPK1 | |
| Ethylene Glycol SCHEMBL11412767 | 0.81 | MAPT (0.46) | TP53TSHRMAPTTDP1MAPK1 | |
| SCHEMBL3453488 | 0.81 | MAPT (0.49) | TP53TSHRMAPTTDP1MAPK1 | |
| SCHEMBL28268466 | 0.80 | TDP1 (0.46) | HTTTP53TSHRMAPTTDP1 | |
| Terephthalic Acid SCHEMBL29140933 | 0.80 | HTT (0.51) | HTTTP53TSHRPLA2G4BTDP1 | |
| SCHEMBL2219999 | 0.79 | HTT (0.49) | HTTTP53TSHRPLA2G4BMAPT | |
| SCHEMBL1553164 | 0.79 | TDP1 (0.53) | HTTTP53TSHRPLA2G4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318837-A | BLEND OF SATURATED POLYESTER, UNDATURATED POLYESTER AND POLYISOCYANATE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4204987-A | Aqueous polyester dispersion for adhering vinyl film to wood | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1980-05-27 | — | — | US | disclosed |