Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419671 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL8421516 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL8420092 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL8419619 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL838569 | 0.77 | — | — | |
| SCHEMBL8419939 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL8421244 | 0.77 | — | — | |
| SCHEMBL17138297 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL8421324 | 0.77 | — | — | |
| SCHEMBL3888328 | 0.75 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363925-A | PALLADIUM COMPLEX AND A PHOSPHINE OR PHOSPHITE CATALYZED REACTION OF A DISILANE AND AN AROMATIC HALIDE | BASF AKTIENGESELLSCHAFT (DE) | 1982-12-14 | — | — | US | disclosed |