SCHEMBL11237786

SCHEMBL11237786

CCOc1cccc(C)c1-n1cc(C#N)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.41
PDE5A O76074 2/20 0.39
DAO P14920 1/20 0.38
GRK6 P43250 1/20 0.38
POLB P06746 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2B Q13224 1/20 0.37
BCAT1 P54687 3/20 0.36
BCAT2 O15382 1/20 0.36
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11274140 0.87 L3MBTL1 (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11245190 0.85 GAA (0.63) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11249041 0.83 GAA (0.55) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11255750 0.82 L3MBTL1 (0.50) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11258384 0.79 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11243717 0.79 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11271035 0.79 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11248107 0.79 L3MBTL1 (0.61) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11268199 0.77 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11243626 0.77 GAA (0.57) GAAL3MBTL1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed