Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA6 | P23280 | 5/20 | 0.33 |
| ▸ | CA7 | P43166 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA5A | P35218 | 4/20 | 0.33 |
| ▸ | CA3 | P07451 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | CASP2 | P42575 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | F13A1 | P00488 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | THPO | P40225 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228573 | 0.90 | TDP1 (0.35) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL11236612 | 0.85 | TDP1 (0.48) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL11233371 | 0.77 | TDP1 (0.37) | TDP1CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL11271137 | 0.74 | TDP1 (0.32) | TDP1 | |
| SCHEMBL3132997 | 0.71 | CA12 (0.41) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL430987 | 0.71 | — | — | |
| SCHEMBL13154379 | 0.69 | CA12 (0.71) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL28843802 | 0.69 | CA12 (0.65) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL6756172 | 0.69 | CA12 (0.65) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL5956353 | 0.69 | CA12 (0.65) | TDP1CA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326054-A | ANTIBIOTIC AND ANTITUMOR AGENT | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-04-20 | — | — | US | disclosed |