Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA6 | P23280 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CASP2 | P42575 | 2/20 | 0.44 |
| ▸ | F13A1 | P00488 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237797 | 0.85 | TDP1 (0.37) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL3132997 | 0.85 | CA12 (0.41) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL11228573 | 0.82 | TDP1 (0.35) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL11233371 | 0.80 | TDP1 (0.37) | TDP1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL832891 | 0.72 | TDP1 (0.62) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL2421695 | 0.71 | DNM1 (0.35) | MEN1KMT2ATSHR | |
| SCHEMBL5167308 | 0.71 | PLA2G1B (0.36) | TDP1MEN1KMT2ATSHR | |
| SCHEMBL7991030 | 0.69 | TDP1 (0.58) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL24770611 | 0.69 | TDP1 (0.58) | TDP1CA12CA6CA7CA9 | |
| SCHEMBL5078140 | 0.69 | CHRM2 (0.42) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326054-A | ANTIBIOTIC AND ANTITUMOR AGENT | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-04-20 | — | — | US | disclosed |