SCHEMBL1123811

SCHEMBL1123811

OC(S)C(O)CCS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31312609 0.82 ANPEP (0.32)
Methane SCHEMBL7614864 0.79 ANPEP (0.31)
SCHEMBL6665918 0.75
SCHEMBL23584388 0.73
SCHEMBL94684 0.72
SCHEMBL9275989 0.72
SCHEMBL6672056 0.71
SCHEMBL6669244 0.71
SCHEMBL6985282 0.69 LMNA (0.34)
SCHEMBL20471563 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3667325-B1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORP (US) 2023-10-04 EP claimed
US-20230243845-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2023-08-03 US claimed
US-20220390455-A1 M-PROTEIN ASSAYS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2022-12-08 US claimed
CN-115298549-A M protein assay and uses thereof 百时美施贵宝公司 2022-11-04 CN claimed
EP-3667325-A1 INTEGRITY TESTING OF HAIR SAMPLES Psychemedics Corporation (US) 2020-06-17 EP claimed
EP-3039432-B1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORP (US) 2019-10-09 EP claimed
EP-3126826-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS Mayo Foundation for Medical Education and Research (US) 2017-02-08 EP claimed
US-20170023584-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2017-01-26 US claimed
WO-2016161360-A1 EFFECTIVE HAIR STYLING COMPOSITIONS AND PROCESSES NUTECH VENTURES (US) 2016-10-06 WO claimed
EP-3039432-A2 INTEGRITY TESTING OF HAIR SAMPLES Psychemedics Corporation (US) 2016-07-06 EP claimed
US-9261522-B2 Integrity testing of hair samples PSYCHEMEDICS CORPORATION (US) 2016-02-16 US claimed
US-20150293132-A1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORPORATION 2015-10-15 US claimed
WO-2015154052-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2015-10-08 WO claimed
US-8986939-B1 Integrity testing of hair samples PSYCHEMEDICS CORPORATION (US) 2015-03-24 US claimed
WO-2015031676-A2 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORPORATION (US) 2015-03-05 WO claimed
US-20150064719-A1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORPORATION 2015-03-05 US claimed
EP-0486622-A4 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM 1992-08-12 EP claimed
EP-0486622-A1 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM RHOMED, INCORPORATED (US) 1992-05-27 EP claimed
WO-1991001754-A1 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM RHODES BUCK A (US) 1991-02-21 WO claimed
EP-3523647-B1 IDENTIFICATION AND MONITORING OF CLEAVED IMMUNOGLOBULINS BY MOLECULAR MASS MAYO FOUND MEDICAL EDUCATION & RES (US) 2024-06-26 EP disclosed
US-11946937-B2 Identification and monitoring of apoptosis inhibitor of macrophage MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2024-04-02 US disclosed
EP-3667325-B1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORP (US) 2023-10-04 EP disclosed
US-20230243845-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2023-08-03 US disclosed
EP-4175967-A2 TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF Life Technologies Corporation (US) 2023-05-10 EP disclosed
US-11604196-B2 Isotyping immunoglobulins using accurate molecular mass MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2023-03-14 US disclosed
US-20220390455-A1 M-PROTEIN ASSAYS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2022-12-08 US disclosed
CN-115298549-A M protein assay and uses thereof 百时美施贵宝公司 2022-11-04 CN disclosed
EP-4004556-A1 IONISATION CONTROL The Binding Site Group Limited (GB) 2022-06-01 EP disclosed
US-20220034899-A1 ANTIBODY QUANTIFICATION IN BIOLOGICAL SAMPLES Ichnos Sciences SA (CH) 2022-02-03 US disclosed
WO-2022006368-A2 TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF Life Technologies Corporation (US) 2022-01-06 WO disclosed
US-20220002716-A1 TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF Life Technologies Corporation 2022-01-06 US disclosed
US-10955420-B2 Identification and monitoring of cleaved immunoglobulins by molecular mass MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2021-03-23 US disclosed
WO-2021019211-A1 IONISATION CONTROL THE BINDING SITE GROUP LIMITED (GB) 2021-02-04 WO disclosed
EP-3126826-B1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUND MEDICAL EDUCATION & RES (US) 2020-12-16 EP disclosed
US-10828246-B2 Effective hair styling compositions and processes NUTECH VENTURES (US) 2020-11-10 US disclosed
US-20200341003-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2020-10-29 US disclosed
US-20200292556-A1 IDENTIFICATION AND MONITORING OF APOPTOSIS INHIBITOR OF MACROPHAGE MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2020-09-17 US disclosed
US-20200284800-A1 IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J CHAINS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2020-09-10 US disclosed
US-20200271663-A1 IDENTIFICATION AND MONITORING OF ACID HYDROLYSIS PRODUCTS OF IMMUNOGLOBULIN HEAVY CHAINS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2020-08-27 US disclosed
US-10753945-B2 Isotyping immunoglobulins using accurate molecular mass MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2020-08-25 US disclosed
EP-3681907-A1 IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J CHAINS Mayo Foundation for Medical Education and Research (US) 2020-07-22 EP disclosed
EP-3682249-A1 IDENTIFICATION AND MONITORING OF ACID HYDROLYSIS PRODUCTS OF IMMUNOGLOBULIN HEAVY CHAINS Mayo Foundation for Medical Education and Research (US) 2020-07-22 EP disclosed
EP-3681528-A1 IDENTIFICATION AND MONITORING OF APOPTOSIS INHIBITOR OF MACROPHAGE Mayo Foundation for Medical Education and Research (US) 2020-07-22 EP disclosed
US-10690676-B2 Quantifying monoclonal antibody therapeutics by LC-MS/MS Mayo Roundation for Medical Education and Research (US) 2020-06-23 US disclosed
EP-3667325-A1 INTEGRITY TESTING OF HAIR SAMPLES Psychemedics Corporation (US) 2020-06-17 EP disclosed
EP-3039432-B1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORP (US) 2019-10-09 EP disclosed
EP-3523647-A1 IDENTIFICATION AND MONITORING OF CLEAVED IMMUNOGLOBULINS BY MOLECULAR MASS Mayo Foundation for Medical Education and Research (US) 2019-08-14 EP disclosed
US-20190195888-A1 IDENTIFICATION AND MONITORING OF CLEAVED IMMUNOGLOBULINS BY MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2019-06-27 US disclosed
US-10267806-B2 Isotyping immunoglobulins using accurate molecular mass MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2019-04-23 US disclosed
WO-2019055632-A1 IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J CHAINS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2019-03-21 WO disclosed
WO-2019055634-A1 IDENTIFICATION AND MONITORING OF APOPTOSIS INHIBITOR OF MACROPHAGE MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2019-03-21 WO disclosed
WO-2019055631-A1 IDENTIFICATION AND MONITORING OF ACID HYDROLYSIS PRODUCTS OF IMMUNOGLOBULIN HEAVY CHAINS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2019-03-21 WO disclosed
US-20180106815-A1 QUANTIFYING MONOCLONAL ANTIBODY THERAPEUTICS BY LC-MS/MS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2018-04-19 US disclosed
WO-2018049001-A1 IDENTIFICATION AND MONITORING OF CLEAVED IMMUNOGLOBULINS BY MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2018-03-15 WO disclosed
EP-3175242-A1 QUANTIFYING MONOCLONAL ANTIBODY THERAPEUTICS BY LC-MS/MS Mayo Foundation for Medical Education and Research (US) 2017-06-07 EP disclosed
US-20170095409-A1 EFFECTIVE HAIR STYLING COMPOSITIONS AND PROCESSES NUTECH VENTURES 2017-04-06 US disclosed
EP-3126826-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS Mayo Foundation for Medical Education and Research (US) 2017-02-08 EP disclosed
US-20170023584-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2017-01-26 US disclosed
WO-2016161360-A1 EFFECTIVE HAIR STYLING COMPOSITIONS AND PROCESSES NUTECH VENTURES (US) 2016-10-06 WO disclosed
EP-3039432-A2 INTEGRITY TESTING OF HAIR SAMPLES Psychemedics Corporation (US) 2016-07-06 EP disclosed
US-9261522-B2 Integrity testing of hair samples PSYCHEMEDICS CORPORATION (US) 2016-02-16 US disclosed
WO-2016018978-A1 QUANTIFYING MONOCLONAL ANTIBODY THERAPEUTICS BY LC-MS/MS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2016-02-04 WO disclosed
US-20150293132-A1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORPORATION 2015-10-15 US disclosed
WO-2015154052-A1 ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2015-10-08 WO disclosed
EP-2637026-B1 Non-proteolytic method for the determination of analytes in keratinized structures PSYCHEMEDICS CORP (US) 2015-09-30 EP disclosed
US-8986939-B1 Integrity testing of hair samples PSYCHEMEDICS CORPORATION (US) 2015-03-24 US disclosed
US-20150064719-A1 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORPORATION 2015-03-05 US disclosed
WO-2015031676-A2 INTEGRITY TESTING OF HAIR SAMPLES PSYCHEMEDICS CORPORATION (US) 2015-03-05 WO disclosed
EP-2637026-A1 Non-proteolytic method for the determination of analytes in keratinized structures Psychemedics Corporation (US) 2013-09-11 EP disclosed
EP-2283367-B1 NON-PROTEOLYTIC METHOD FOR THE DETERMINATION OF ANALYTES IN KERATINIZED STRUCTURES PSYCHEMEDICS CORP (US) 2013-06-12 EP disclosed
US-8435747-B2 Non-proteolytic method for the determination of analytes in keratinized structures PSYCHEMEDICS CORPORATION (US) 2013-05-07 US disclosed
US-8329417-B2 Non-proteolytic method for the determination of analytes in keratinized structures PSYCHEMEDICS CORPORATION (US) 2012-12-11 US disclosed
US-20120094309-A1 NON-PROTEOLYTIC METHOD FOR THE DETERMINATION OF ANALYTES IN KERATINIZED STRUCTURES PSYCHEMEDICS CORPORATION (US) 2012-04-19 US disclosed
US-8084215-B2 Non-proteolytic method for the determination of analytes in keratinized structures PSYCHEMEDICS CORPORATION (US) 2011-12-27 US disclosed
US-20110104714-A1 NON-PROTEOLYTIC METHOD FOR THE DETERMINATION OF ANALYTES IN KERATINIZED STRUCTURES PSYCHEMEDICS CORPORATION 2011-05-05 US disclosed
EP-2283367-A1 NON-PROTEOLYTIC METHOD FOR THE DETERMINATION OF ANALYTES IN KERATINIZED STRUCTURES Psychemedics Corporation (US) 2011-02-16 EP disclosed
WO-2009134852-A1 NON-PROTEOLYTIC METHOD FOR THE DETERMINATION OF ANALYTES IN KERATINIZED STRUCTURES PSYCHEMEDICS CORPORATION (US) 2009-11-05 WO disclosed
US-20090269791-A1 NON-PROTEOLYTIC METHOD FOR THE DETERMINATION OF ANALYTES IN KERATINIZED STRUCTURES PSYCHEMEDICS CORPORATION (US) 2009-10-29 US disclosed
US-6949344-B1 Hair analysis method PSYCHEMICAL CORPORATION (US) 2005-09-27 US disclosed
US-6582924-B1 Hair analysis method PSYCHEMEDICS CORPORATION 2003-06-24 US disclosed
US-6350582-B1 DETECTING THE PRESENCE OF AN ANALYTE THAT BECOMES EMBEDDED IN HAIR, FINGERNAILS, AND TOENAILS BY PREPARING A MIXTURE WITH DITHIOTHREITOL OR DITHIOERYTHRITOL, AND A PROTEASE ENZYME THAT DIGEST KERITIN; INCUBATE THE MIXTURE AND ANALYSIS PSYCHEMEDICS CORPORATION 2002-02-26 US disclosed
US-6022693-A DETECTION OF BLOOD ANALYTE EMBEDDED IN KERATINIZED STRUCTURE; PREPARING SOLUTION COMPRISING DIGESTIVE ENZYME, KERATINIZED STRUCTURE, DITHIOTHREITOL AND DITHIOERYTHRITOL; DIGEST, ADD A COPPER SALT, AND ANALYZE BY IMMUOASSAY PSYCHEMEDICS CORPORATION (US) 2000-02-08 US disclosed
EP-0634014-B1 Method for detecting marijuana in a hair sample PSYCHEMEDICS CORP (US) 1999-12-29 EP disclosed
EP-0486622-B1 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM RHOMED INC (US) 1998-11-04 EP disclosed
US-RE35500-E Direct radiolabeling of antibodies and other proteins with technetium or rhenium ABERLYN CAPITAL MANAGEMENT LIMITED PARTNERSHIP (US) 1997-05-06 US disclosed
US-RE35457-E INCUBATING PROTEIN HAVING DISULFIDE BONDS WITH STANNOUS ION REDUCING AGENT, PURIFYING, ADDING REDUCING AGENT TO REDUCE RADIONUCLIDE, ADDING RADIONUCLIDE, FORMING COMPLEX BETWEEN REDUCED PROTEIN AND REDUCED RADIONUCLIDE ABERLYN CAPITAL MANAGEMENT LIMITED PARTNERSHIP (US) 1997-02-18 US disclosed
EP-0555440-B1 HAIR ANALYSIS METHOD PSYCHEMEDICS CORP (US) 1996-08-28 EP disclosed
EP-0458594-B1 Analysis of hair PSYCHEMEDICS CORP (US) 1996-06-26 EP disclosed
EP-0634014-A4 HAIR ANALYSIS METHOD. PSYCHEMEDICS CORP (US) 1996-02-07 EP disclosed
US-5466579-A Detection of marijuana intake PSYCHEMEDICS CORPORATION (US) 1995-11-14 US disclosed
EP-0634014-A1 HAIR ANALYSIS METHOD PSYCHEMEDICS CORPORATION (US) 1995-01-18 EP disclosed
WO-1994018561-A1 HAIR ANALYSIS METHOD PSYCHEMEDICS CORPORATION (US) 1994-08-18 WO disclosed
US-5324642-A Ligand assays of enzymatic hair digests PSYCHEMEDICS CORPORATION (US) 1994-06-28 US disclosed
EP-0555440-A4 1994-03-23 EP disclosed
US-5277893-A Complexing with a tin agent RHOMED, INCORPORATED (US) 1994-01-11 US disclosed
EP-0555440-A1 HAIR ANALYSIS METHOD. PSYCHEMEDICS CORP (US) 1993-08-18 EP disclosed
WO-1993003368-A1 HAIR ANALYSIS METHOD PSYCHEMEDICS CORPORATION (US) 1993-02-18 WO disclosed
EP-0486622-A4 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM 1992-08-12 EP disclosed
EP-0486622-A1 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM RHOMED, INCORPORATED (US) 1992-05-27 EP disclosed
US-5102990-A Incubating the protein containing monosulfide or disulfide bonds with a tin/II/ agent, purifying, adding a second tin/II/ agent and sulfur-containing complexes, adding radionucleotide RHOMED INCORPORATED (US) 1992-04-07 US disclosed
US-5078985-A Reduction With Stannous Salts Or Other Sulfide Reducing Agents RHOMED, INCORPORATED (US) 1992-01-07 US disclosed
EP-0458594-A2 Analysis of hair PSYCHEMEDICS CORPORATION (US) 1991-11-27 EP disclosed
WO-1991001754-A1 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM RHODES BUCK A (US) 1991-02-21 WO disclosed
WO-1991001754-A1 DIRECT RADIOLABELING OF ANTIBODIES AND OTHER PROTEINS WITH TECHNETIUM OR RHENIUM RHODES BUCK A (US) 1991-02-21 WO disclosed