Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002361 | 0.82 | MEN1 (0.48) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL29512533 | 0.82 | MEN1 (0.51) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL10510963 | 0.80 | MEN1 (0.50) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL10739338 | 0.80 | MEN1 (0.80) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL11156046 | 0.79 | POLB (0.55) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL9069057 | 0.78 | MEN1 (0.47) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL11092759 | 0.76 | CYP3A4 (0.52) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL17289538 | 0.76 | POLB (0.58) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL10734466 | 0.74 | KMT2A (0.78) | MEN1KMT2ATDP1HSP90AA1POLB | |
| SCHEMBL11286281 | 0.74 | CYP19A1 (0.45) | MEN1KMT2ATDP1CYP19A1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359470-A | Acylated triazolyl-γ-fluoropinacolyl derivatives and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |