SCHEMBL11286281

SCHEMBL11286281

OC(c1ccc(F)cc1)C(c1ccc(Cl)cc1Cl)n1cncn1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 15/20 0.45
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
IDO1 P14902 1/20 0.38
ADRA2C P18825 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11038306 0.91 CYP19A1 (0.45) CYP19A1KMT2AMEN1TDP1IDO1
SCHEMBL10510963 0.80 MEN1 (0.50) CYP19A1KMT2AMEN1TDP1ADRA2C
SCHEMBL10507165 0.80 CYP19A1 (0.46) CYP19A1KMT2AMEN1TDP1IDO1
SCHEMBL8769060 0.78 CYP19A1 (0.44) CYP19A1
SCHEMBL10506374 0.77 CYP19A1 (0.49) CYP19A1KMT2AMEN1TDP1ADRA2C
SCHEMBL10911920 0.75 MEN1 (0.50) CYP19A1KMT2AMEN1TDP1ADRA2C
SCHEMBL11238199 0.74 MEN1 (0.54) CYP19A1KMT2AMEN1TDP1ADRA2C
SCHEMBL11288116 0.74 CYP19A1 (0.48) CYP19A1KMT2AMEN1TDP1
SCHEMBL9385857 0.73 MEN1 (0.49) CYP19A1KMT2AMEN1TDP1ADRA2C
SCHEMBL9069057 0.73 MEN1 (0.47) CYP19A1KMT2AMEN1TDP1ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0048548-A1 Pharmaceutical compositions of fungicidal triazole derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-03-31 EP disclosed