SCHEMBL112382

SCHEMBL112382

Nc1cc(F)ccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4372816 0.97 ALDH1A1 (0.59)
SCHEMBL28749668 0.86 TDP1 (0.50)
SCHEMBL15234491 0.79 CYP1A1 (0.51)
SCHEMBL15234523 0.79 CYP1A1 (0.51)
Boric Acid SCHEMBL28141304 0.79 ALDH1A1 (0.42)
SCHEMBL29476041 0.79
SCHEMBL103128 0.79
SCHEMBL25212486 0.78 ALDH1A1 (0.50)
SCHEMBL30927149 0.78 ALDH1A1 (0.50)
SCHEMBL8181149 0.77 TDP1 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798252-A Method for preparing N-ortho-acyl substituted nitrogen-containing heterocyclic compound and amine-shrinking iron (II) complex thereof 中国石油化工股份有限公司 2025-04-11 CN claimed
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-119143751-A N-ortho-acyl substituted nitrogen-containing heterocyclic compound and preparation method of amine-shrinking iron (II) complex thereof 中国石油化工股份有限公司 2024-12-17 CN claimed
CN-119144344-A Liquid crystal compound containing 2, 5-difluorobenzene alkyne, synthesis method and liquid crystal composition 西安近代化学研究所 2024-12-17 CN claimed
CN-119143750-A Preparation method of N-ortho-alkyl substituted 1, 10-phenanthroline compound and catalyst prepared by same 中国石油化工股份有限公司 2024-12-17 CN claimed
CN-118183708-A Method for preparing fluorocarbon material by using fluorine-containing polymer 重庆大学锂电及新材料遂宁研究院 2024-06-14 CN claimed
CN-117623987-A Isothiocyanate liquid crystal compound containing 2, 5-difluoro substituted benzene and synthesis method 西安近代化学研究所 2024-03-01 CN claimed
CN-114031974-A Ink for ink jet printing and electroluminescent device 广东聚华印刷显示技术有限公司 2022-02-11 CN claimed
CN-111269247-B Preparation method of buprofezin drug molecule with escherichia coli inhibition effect 河南科技大学第一附属医院 2020-11-24 CN claimed
CN-110642741-A Functionalized benzamide derivatives as antiviral agents against HBV infection 巴鲁克斯布隆伯格研究所 2020-01-03 CN claimed
US-20020068753-A1 2,3-oxidosqualene-lanosterol cyclase inhibitors HOFFMANN-LA ROCHE INC. 2002-06-06 US claimed
WO-2002042303-A2 ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS AVENTIS PHARMACEUTICALS INC. (US) 2002-05-30 WO claimed
WO-2002020483-A1 PIPERIDINE DERIVATIVES FOR USE 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2002-03-14 WO claimed
WO-2002012442-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR NEUROGEN CORPORATION (US) 2002-02-14 WO claimed
EP-0667337-B1 Method for preparing fluoroanilines CLARIANT GMBH (DE) 1998-01-21 EP claimed
US-5498794-A Process for preparing fluoroanilines HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-12 US claimed
EP-0667337-A1 Method for preparing fluoroanilines HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-16 EP claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed