Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537649 | 0.92 | KCNH2 (0.55) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL11236930 | 0.84 | SLC22A2 (0.51) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL10638784 | 0.80 | BLM (0.55) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL11536797 | 0.79 | KCNH2 (0.44) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL10635538 | 0.79 | BLM (0.52) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL10956631 | 0.78 | SLC22A2 (0.43) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL9581143 | 0.77 | CYP3A4 (0.60) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL10633053 | 0.77 | SLC22A2 (0.48) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL10516737 | 0.76 | CYP3A4 (0.50) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL10952757 | 0.75 | SLC22A2 (0.40) | SLC22A2SLC22A1PGRTHRBADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356177-A | Myocardium-protecting pyridine derivatives having an anti-arrhythmic activity and an activity as blood-platelets antiaggregants | C.M. INDUSTRIES (FR) | 1982-10-26 | — | — | US | disclosed |