Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238412 | 0.92 | SLC22A2 (0.51) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL11236930 | 0.89 | SLC22A2 (0.51) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL11536797 | 0.86 | KCNH2 (0.44) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL10638784 | 0.85 | BLM (0.55) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL10956631 | 0.82 | SLC22A2 (0.43) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL10952757 | 0.81 | SLC22A2 (0.40) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL9581143 | 0.81 | CYP3A4 (0.60) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL10633053 | 0.81 | SLC22A2 (0.48) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL10516737 | 0.80 | CYP3A4 (0.50) | KCNH2BLMCYP3A4TSHRSLC22A2 | |
| SCHEMBL18293530 | 0.79 | SMN1; SMN2 (0.41) | KCNH2BLMCYP3A4TSHRSLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153797-A | α-Aryl-α, α-bis[ω- (disubstituted amino)alkyl]acetamides and related compounds | G. D. SEARLE & CO. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4107205-A | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds | G. D. SEARLE & CO. (US) | 1978-08-15 | — | — | US | disclosed |