SCHEMBL11238440

SCHEMBL11238440

Cc1ccc(CCC2(Cn3ccnc3)OCC(C)(C)CO2)cc1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HMOX1 P09601 4/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240947 0.93 HMOX1 (0.54) HMOX1
SCHEMBL11251358 0.89 HMOX1 (0.69) HMOX1
SCHEMBL11253728 0.89 HMOX1 (0.61) HMOX1
SCHEMBL11239942 0.89 HMOX1 (0.49) HMOX1
SCHEMBL11238169 0.89 HMOX1 (0.60) HMOX1
SCHEMBL10247103 0.89 HMOX1 (0.77) HMOX1
SCHEMBL11234153 0.88 HMOX1 (0.60) HMOX1
Hydrochloric Acid SCHEMBL11245515 0.88 HMOX1 (0.70) HMOX1
Bromide SCHEMBL11238088 0.88 HMOX1 (0.59) HMOX1
SCHEMBL11229992 0.88 HMOX1 (0.53) HMOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049565-A2 Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1982-04-14 EP disclosed
US-4321272-A Derivatives of substituted N-alkylimidazoles SYNTEX (U.S.A.) INC. (US) 1982-03-23 US disclosed