SCHEMBL11238548

SCHEMBL11238548

CC(C)(C)C(=NO)n1cncn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.39
NPC1 O15118 4/20 0.39
MAPT P10636 4/20 0.39
PKM P14618 4/20 0.39
HTT P42858 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
MITF O75030 1/20 0.39
ATM Q13315 3/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 4/20 0.36
HPGD P15428 3/20 0.34
TP53 P04637 2/20 0.34
POLB P06746 1/20 0.34
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32
XBP1 P17861 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
S1PR2 O95136 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11238546 1.00 RAB9A (0.39) RAB9ANPC1MAPTPKMHTT
SCHEMBL11247760 0.82 MEN1 (0.34) RAB9ANPC1MAPTPKMHTT
SCHEMBL11238687 0.82 MEN1 (0.34) RAB9ANPC1MAPTPKMHTT
SCHEMBL11247765 0.82 MEN1 (0.34) RAB9ANPC1MAPTPKMHTT
SCHEMBL11238692 0.82 MEN1 (0.34) RAB9ANPC1MAPTPKMHTT
SCHEMBL11241283 0.80 MEN1 (0.36) RAB9ANPC1MAPTPKMHTT
SCHEMBL11245126 0.80 MEN1 (0.33) RAB9ANPC1MAPTPKMHTT
SCHEMBL11241288 0.80 MEN1 (0.36) RAB9ANPC1MAPTPKMHTT
SCHEMBL11237453 0.80 RAB9A (0.33) RAB9ANPC1MAPTPKMHTT
SCHEMBL11245115 0.80 MEN1 (0.33) RAB9ANPC1MAPTPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed
EP-0005780-A1 N,N'-asymmetrically substituted thio-bis-amines, process for their preparation and their use as insecticides, acaricides and nematocides BAYER AG (DE) 1979-12-12 EP disclosed