Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101543 | 1.00 | TYR (0.45) | TYRESR1ADRA2AADORA3TACR2 | |
| SCHEMBL17965869 | 1.00 | TYR (0.45) | TYRESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27600500 | 0.93 | HTT (0.42) | TYRESR1TP53CYP19A1KDM4E | |
| SCHEMBL11202288 | 0.88 | TYR (0.49) | TYRESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11660171 | 0.88 | TYR (0.49) | TYRESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8891283 | 0.88 | TYR (0.49) | TYRESR1ADRA2AADORA3TACR2 | |
| SCHEMBL688489 | 0.87 | TYR (0.45) | TYRESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2457616 | 0.86 | ALDH1A1 (0.38) | TYRESR1TP53KDM4EALDH1A1 | |
| SCHEMBL29194349 | 0.82 | TYR (0.42) | TYRESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27822394 | 0.80 | HPGD (0.46) | TYRESR1TP53CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337369-A | PREPARED BY REACTION OF ISOBUTYLENE WITH ALKYLPHENOL, ION EXCHANGE RESIN CATALYST, TRIOXANE | TEXACO INC. (US) | 1982-06-29 | — | — | US | claimed |
| US-4356330-A | DISCOLORATION INHIBITION OF POLYETHERURETHANE FOAMS | TEXACO INC. (US) | 1982-10-26 | — | — | US | disclosed |
| US-4337369-A | PREPARED BY REACTION OF ISOBUTYLENE WITH ALKYLPHENOL, ION EXCHANGE RESIN CATALYST, TRIOXANE | TEXACO INC. (US) | 1982-06-29 | — | — | US | disclosed |