Sugi Predict

Sugi Predict / Compounds / SCHEMBL112391

SCHEMBL112391

SCHEMBL112391

Cc1cc(N)cc(C)c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.53
▸ TSHR P16473 5/20 0.53
▸ PDE10A Q9Y233 1/20 0.43
▸ CASP1 P29466 2/20 0.41
▸ CYP3A4 P08684 5/20 0.40
▸ TDP1 Q9NUW8 4/20 0.40
▸ TP53 P04637 2/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ THRB P10828 2/20 0.37
▸ LMNA P02545 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ ACHE P22303 1/20 0.35
▸ POLB P06746 2/20 0.35
▸ CD44 P16070 1/20 0.35
▸ GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23198661 0.97 ALDH1A1 (0.50) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL5175966 0.84 TDP1 (0.48) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL31141515 0.84 TDP1 (0.48) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL10177109 0.82 ALDH1A1 (0.43) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL5306395 0.80 ALDH1A1 (0.41) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL29673601 0.80 TSHR (0.52) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL9743570 0.80 TSHR (0.52) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL13584637 0.80 MAPT (0.50) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL21277503 0.80 ALDH1A1 (0.41) ALDH1A1TSHRPDE10ACASP1CYP3A4
SCHEMBL29548102 0.80 MAPT (0.50) ALDH1A1TSHRPDE10ACASP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 — — CN claimed
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2024-08-27 — — US claimed
CN-118420612-A Target protein degradation compound based on CDK4/6 inhibitor and preparation method and application thereof 沈阳药科大学 2024-08-02 — — CN claimed
CN-118290283-A Preparation method and application of near-infrared piezochromic material with AIE (AIE) property 山东海化集团有限公司 2024-07-05 — — CN claimed
CN-117430733-A Bimetallic catalyst based on acylhydrazone pyrene skeleton, and preparation method and application thereof 万华化学集团股份有限公司 2024-01-23 — — CN claimed
CN-117209632-A Preparation method of nickel catalyst for olefin polymerization 浙江巨化技术中心有限公司 2023-12-12 — — CN claimed
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2022-06-30 — — US claimed
WO-2022134489-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUND 福建中欣氟材高宝科技有限公司 2022-06-30 — — WO claimed
CN-112608212-B Full continuous flow synthesis process of fluorine-containing aromatic compound 福建中欣氟材高宝科技有限公司 2022-02-08 — — CN claimed
CN-112608212-A Full continuous flow synthesis process of fluorine-containing aromatic compound 福建高宝矿业有限公司 2021-04-06 — — CN claimed
CN-108314647-B Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative 华中科技大学 2020-06-26 — — CN claimed
CN-110003207-A The imide fluorescent dye and preparation method thereof that a kind of gulf position phenoxy group replaces 天津大学 2019-07-12 — — CN claimed
CN-108314647-A A kind of preparation method of quinoline -2- formic acid and quinoline -2- formic acid derivates 华中科技大学 2018-07-24 — — CN claimed
CN-104743568-B A kind of synthetic method of 49 molecular sieves of MCM 中国石油化工股份有限公司 2017-03-29 — — CN claimed
CN-104743570-B A kind of synthetic method of MCM 56 molecular sieve 中国石油化工股份有限公司 2017-03-01 — — CN claimed
CN-106146409-A The preparation method of 2-arylthio-5-halogenated pyrimidine ketones derivant and the application as anti-hepatic-B virus medicine thereof 北京大学 2016-11-23 — — CN claimed
CN-103771435-B A kind of method of synthesizing MCM-22 molecular sieve SINOPEC CORP. (CN) 2015-10-28 — — CN claimed
CN-104743570-A A synthetic method of an MCM-56 molecular sieve CHINA PETROLEUM & CHEMICAL 2015-07-01 — — CN claimed
CN-104743568-A A synthetic method of an MCM-49 molecular sieve CHINA PETROLEUM & CHEMICAL 2015-07-01 — — CN claimed
CN-103771435-A Method for synthesis of MCM-22 molecular sieve CHINA PETROLEUM & CHEMICAL 2014-05-07 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS AHR, FGFR2, FGFR1 ALDH1A1 1785/4885TSHR 517/4885PDE10A 2500/4885
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds AHR, FGFR2, FGFR1 ALDH1A1 1785/4885TSHR 517/4885PDE10A 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.