Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PHLPP2 | Q6ZVD8 | 5/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 3/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | BPTF | Q12830 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15293552 | 1.00 | NPC1 (0.59) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL11239208 | 1.00 | NPC1 (0.59) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL6123730 | 0.91 | RPS6KA3 (0.54) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL14004211 | 0.91 | RPS6KA3 (0.54) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL12758032 | 0.91 | RPS6KA3 (0.54) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL8375101 | 0.90 | RPS6KA3 (0.52) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL11242221 | 0.89 | BRD4 (0.64) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL11242226 | 0.89 | BRD4 (0.64) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL19970680 | 0.85 | MAPT (0.59) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL28222655 | 0.84 | MAPT (0.57) | NPC1MAPTRAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323682-A | BLEACHING CATALYSTS | CIBA GEIGY AG (CH) | 1982-04-06 | — | — | US | disclosed |
| US-4202698-A | DYE BLEACH CATALYSTS | CIBA-GEIGY AG (CH) | 1980-05-13 | — | — | US | disclosed |