Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.64 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.64 |
| ▸ | BRD2 | P25440 | 2/20 | 0.64 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.64 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.60 |
| ▸ | BPTF | Q12830 | 1/20 | 0.60 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.60 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.60 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.58 |
| ▸ | PHLPP2 | Q6ZVD8 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242221 | 1.00 | BRD4 (0.64) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL15293552 | 0.89 | NPC1 (0.59) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL11239206 | 0.89 | NPC1 (0.59) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL11239208 | 0.89 | NPC1 (0.59) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL12486693 | 0.87 | RPS6KA3 (0.62) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL12486691 | 0.87 | RPS6KA3 (0.62) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL23787102 | 0.84 | MAPT (0.66) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL20271467 | 0.84 | MAPT (0.66) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL12758032 | 0.83 | RPS6KA3 (0.54) | BRD4BRD3BRD2BRDTCREBBP | |
| SCHEMBL14004211 | 0.83 | RPS6KA3 (0.54) | BRD4BRD3BRD2BRDTCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323682-A | BLEACHING CATALYSTS | CIBA GEIGY AG (CH) | 1982-04-06 | — | — | US | disclosed |
| US-4202698-A | DYE BLEACH CATALYSTS | CIBA-GEIGY AG (CH) | 1980-05-13 | — | — | US | disclosed |