Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233207 | 0.92 | TDP1 (0.52) | TDP1GCGRRAB9AALDH1A1PYGL | |
| SCHEMBL11234781 | 0.92 | TDP1 (0.57) | TDP1GCGRRAB9AALDH1A1PYGL | |
| SCHEMBL11241073 | 0.84 | TDP1 (0.55) | TDP1GCGRRAB9AALDH1A1NPC1 | |
| SCHEMBL396610 | 0.84 | TDP1 (0.61) | TDP1GCGRRAB9AALDH1A1PYGL | |
| SCHEMBL11244515 | 0.83 | TDP1 (0.63) | TDP1GCGRRAB9AALDH1A1PYGL | |
| SCHEMBL11235108 | 0.82 | TDP1 (0.40) | TDP1 | |
| SCHEMBL11244568 | 0.82 | TDP1 (0.58) | TDP1GCGRRAB9AALDH1A1PYGL | |
| SCHEMBL11243840 | 0.82 | TDP1 (0.58) | TDP1GCGRRAB9AALDH1A1PYGL | |
| SCHEMBL10906894 | 0.81 | NPC1 (0.43) | RAB9ANPC1 | |
| SCHEMBL11136952 | 0.81 | TDP1 (0.66) | TDP1GCGRRAB9AALDH1A1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | claimed |
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |