Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233207 | 0.86 | TDP1 (0.52) | TDP1LMNANPC1RAB9AGCGR | |
| SCHEMBL11232921 | 0.84 | TDP1 (0.62) | TDP1NPSR1RORCMEN1KMT2A | |
| SCHEMBL11239414 | 0.84 | TDP1 (0.55) | TDP1NPC1RAB9AGCGRALDH1A1 | |
| SCHEMBL10909100 | 0.84 | SLC7A5 (0.44) | NPSR1SLC6A9SLC7A5MEN1KMT2A | |
| SCHEMBL11234781 | 0.80 | TDP1 (0.57) | TDP1NPC1RAB9AGCGRALDH1A1 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.80 | TDP1 (0.70) | TDP1RORCMEN1KMT2ALMNA | |
| SCHEMBL10705614 | 0.78 | TDP1 (0.53) | TDP1NPSR1RORCMEN1KMT2A | |
| SCHEMBL11235108 | 0.77 | TDP1 (0.40) | TDP1 | |
| SCHEMBL11248869 | 0.77 | TDP1 (0.64) | TDP1NPSR1RORCMEN1KMT2A | |
| SCHEMBL11253045 | 0.76 | TDP1 (0.59) | TDP1NPSR1RORCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |