Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077196 | 0.89 | MAPT (0.43) | MAPTTSHRALDH1A1TDP1DCTPP1 | |
| SCHEMBL27709979 | 0.86 | MAPT (0.35) | MAPTTSHRALDH1A1TDP1DCTPP1 | |
| SCHEMBL14786602 | 0.86 | MAPT (0.38) | MAPTALDH1A1TDP1PKMNPC1 | |
| SCHEMBL9125919 | 0.86 | MEN1 (0.37) | MAPTTSHRALDH1A1TDP1DCTPP1 | |
| SCHEMBL1123483 | 0.82 | MAPT (0.42) | MAPTTSHRALDH1A1TDP1DCTPP1 | |
| SCHEMBL3102887 | 0.82 | MAPT (0.40) | MAPTTSHRALDH1A1TDP1DCTPP1 | |
| SCHEMBL3106347 | 0.81 | SMN1; SMN2 (0.35) | MAPTTSHRALDH1A1DCTPP1NPC1 | |
| SCHEMBL18227006 | 0.81 | TSHR (0.38) | MAPTTSHRALDH1A1TDP1DCTPP1 | |
| SCHEMBL628550 | 0.80 | ALDH1A1 (0.41) | MAPTTSHRALDH1A1TDP1NPC1 | |
| SCHEMBL9124844 | 0.78 | MAPT (0.37) | MAPTTSHRALDH1A1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483268-B | The preparation method of a kind of 4,6-bis-chloro-2-methyl-5-nitro pyrimidine | Changzhou University (CN) | 2015-10-14 | — | — | CN | claimed |
| US-20250333418-A1 | PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NOVO NORDISK AS (DK) | 2025-10-30 | — | — | US | disclosed |
| EP-4608835-A1 | PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Novo Nordisk A/S (DK) | 2025-09-03 | — | — | EP | disclosed |
| CN-120129684-A | Purine compound, composition containing same and use thereof | 诺和诺德股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-118946565-A | Substituted fused ring cannabinoid receptor compounds and uses thereof | 长春金赛药业有限责任公司 | 2024-11-12 | — | — | CN | disclosed |
| WO-2024103400-A1 | POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 水木未来(北京)科技有限公司 | 2024-05-23 | — | — | WO | disclosed |
| WO-2024104250-A1 | POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 水木未来(北京)科技有限公司 | 2024-05-23 | — | — | WO | disclosed |
| WO-2024086939-A1 | PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | INVERSAGO PHARMA INC. (CA) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024017227-A1 | SUBSTITUTED FUSED RING CANNABINOID RECEPTOR COMPOUND AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-01-25 | — | — | WO | disclosed |
| EP-3873484-B1 | NOVEL STING AGONISTS | VENENUM BIODESIGN LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-1997035846-A1 | ARYLOXY- AND ARYLTHIO-FUSED PYRIDINES AND PYRIMIDINES AND DERIVATIVES | DUPONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997035539-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
| EP-0768087-A2 | Treating substance abuse withdrawal | ELI LILLY AND COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0764166-A1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | PFIZER INC. (US) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995033750-A1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | PFIZER INC. (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5397781-A | Pyrimidine derivatives | MOCHIDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0561175-A1 | Pyrimidine derivatives and pharmaceutical compostions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-4055411-A | 5-NITRO-PYRIMIDINES | CIBA-GEIGY CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4014677-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3948914-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333418-A1 | PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | CNR1, CNR2, P2RY1 | MAPT 262/4885TSHR 1451/4885ALDH1A1 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.