Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.75 |
| ▸ | CA2 | P00918 | 3/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29245006 | 1.00 | CA1 (0.75) | CA1CA2HDAC1RAB9ANPC1 | |
| SCHEMBL13934091 | 0.92 | CA1 (0.87) | CA1CA2RAB9ANPC1MAPT | |
| SCHEMBL11238983 | 0.87 | MAPT (0.71) | CA1CA2HDAC1RAB9ANPC1 | |
| SCHEMBL17618029 | 0.86 | CA1 (0.77) | CA1CA2RAB9ANPC1MAPT | |
| SCHEMBL12051728 | 0.86 | CA1 (1.00) | CA1CA2RAB9ANPC1MAPT | |
| SCHEMBL1711043 | 0.85 | HDAC1 (0.59) | CA1CA2HDAC1RAB9ANPC1 | |
| SCHEMBL1368686 | 0.85 | NPC1 (0.78) | CA1CA2RAB9ANPC1MAPT | |
| SCHEMBL1845601 | 0.85 | CA1 (0.71) | CA1CA2HDAC1RAB9ANPC1 | |
| SCHEMBL15761719 | 0.84 | CA1 (0.75) | CA1CA2RAB9ANPC1MAPT | |
| SCHEMBL11242935 | 0.84 | CA1 (0.75) | CA1CA2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |