Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.75 |
| ▸ | CA2 | P00918 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15761719 | 1.00 | CA1 (0.75) | CA1CA2MEN1KMT2AMAPK1 | |
| SCHEMBL20183470 | 0.96 | CA1 (0.69) | CA1CA2MEN1KMT2AMAPK1 | |
| SCHEMBL13934091 | 0.92 | CA1 (0.87) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL11247013 | 0.87 | MAPT (0.71) | CA1CA2MEN1KMT2AMAPK1 | |
| SCHEMBL11253516 | 0.86 | MEN1 (0.63) | CA1CA2MEN1KMT2AMAPK1 | |
| SCHEMBL17618029 | 0.86 | CA1 (0.77) | CA1CA2MEN1KMT2AMAPK1 | |
| SCHEMBL12051728 | 0.86 | CA1 (1.00) | CA1CA2MEN1KMT2AMAPK1 | |
| SCHEMBL185028 | 0.85 | MEN1 (0.61) | CA1CA2MEN1KMT2AMAPK1 | |
| SCHEMBL11240016 | 0.84 | CA1 (0.75) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL16211427 | 0.84 | CA1 (0.75) | CA1CA2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4271188-A | SUBSTITUTED ARALKYLANILINES | BEECHAM GROUP LIMITED (GB) | 1981-06-02 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |