Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312984 | 0.86 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL27701334 | 0.84 | SLC6A3 (0.38) | SLC6A3SLC6A2ALDH1A1LMNATSHR | |
| SCHEMBL11237405 | 0.82 | DPP7 (0.37) | SLC6A3SLC6A2SLC6A4DHFRDPP7 | |
| SCHEMBL27916092 | 0.80 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL27566224 | 0.79 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL3289063 | 0.76 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL959206 | 0.75 | — | — | |
| SCHEMBL20651841 | 0.75 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL5765094 | 0.72 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL5502385 | 0.72 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364867-A | URINARY SYSTEM DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4263316-A | ANTISPASMODIC, FOR URINARY DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1981-04-21 | — | — | US | disclosed |