Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143571 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| SCHEMBL858260 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| SCHEMBL141446 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| Ammonia Solution, Strong SCHEMBL28791130 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| SCHEMBL28186389 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| Ethane SCHEMBL9181718 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| SCHEMBL143815 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL8800602 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| SCHEMBL29568445 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAHSD17B10GAA | |
| SCHEMBL6247104 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338248-A | RADIOACTIVE DIAGNOSTIC AGENT | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| EP-0024464-B1 | 2-OXOPROPIONALDEHYDE BIS(THIOSEMICARBAZONE)DERIVATIVES AND THEIR PRODUCTION AND USE | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1982-05-12 | — | — | EP | disclosed |
| US-4287362-A | AS CHELATING AGENTS IN COMBINATION WITH PROTEINS AND A RADIOACTIVE ISOTOPE OF TECHNETIUM FOR DIAGNOSIS | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1981-09-01 | — | — | US | disclosed |
| EP-0024464-A1 | 2-Oxopropionaldehyde bis(thiosemicarbazone)derivatives and their production and use | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1981-03-11 | — | — | EP | disclosed |