Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243329 | 0.84 | GSK3A (0.44) | GSK3AGSK3BHPGDCYP2C9CYP2C19 | |
| SCHEMBL11244802 | 0.81 | GSK3A (0.42) | GSK3AGSK3BHPGDCYP2C9CYP2C19 | |
| SCHEMBL11243422 | 0.78 | GSK3A (0.50) | GSK3AGSK3BHPGDELANEPOLB | |
| SCHEMBL11237218 | 0.72 | MAPT (0.40) | GSK3AGSK3BHPGDCYP2C9CYP2C19 | |
| SCHEMBL11240497 | 0.71 | GSK3A (0.43) | GSK3AGSK3BHPGDELANEPOLB | |
| SCHEMBL31442507 | 0.70 | GSK3A (0.51) | GSK3AGSK3BHPGDCYP2C9CYP2C19 | |
| SCHEMBL9623389 | 0.64 | POLB (0.56) | GSK3AGSK3BHPGDELANEPOLB | |
| SCHEMBL11618507 | 0.63 | GSK3A (0.39) | GSK3AGSK3BHPGDPOLBKDM4E | |
| SCHEMBL11613139 | 0.63 | GSK3A (0.44) | GSK3AGSK3BHPGDELANEPOLB | |
| SCHEMBL11368074 | 0.63 | ALDH1A1 (0.47) | GSK3AGSK3BHPGDCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326878-A | Herbicidal and plant-growth-regulating 1,2,4-trisubstituted-1,2,4-triazolidin-3,5-dithiones | CHEVRON RESEARCH (US) | 1982-04-27 | — | — | US | disclosed |
| US-4276420-A | PRE- AND POST-EMERGENCE | CHEVRON RESEARCH COMPANY (US) | 1981-06-30 | — | — | US | disclosed |