SCHEMBL11240290

SCHEMBL11240290

CCOC(=O)CCC(F)C(F)(F)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 3/20 0.41
KMT2A Q03164 2/20 0.41
CYP1A2 P05177 1/20 0.40
GAA P10253 3/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 3/20 0.36
APP P05067 1/20 0.36
TRPA1 O75762 1/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
CYP4F2 P78329 2/20 0.34
CYP4A11 Q02928 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
RAB9A P51151 1/20 0.33
NR1I2 O75469 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15536758 0.77 L3MBTL1 (0.52) L3MBTL1POLBKMT2ACYP1A2GAA
SCHEMBL9796946 0.76 L3MBTL1 (0.41) L3MBTL1POLBKMT2ACYP1A2GAA
SCHEMBL11238724 0.74 L3MBTL1 (0.46) L3MBTL1POLBKMT2ACYP1A2GAA
SCHEMBL6116793 0.74 L3MBTL1 (0.46) L3MBTL1POLBKMT2ACYP1A2GAA
SCHEMBL28456840 0.73 L3MBTL1 (0.49) L3MBTL1POLBKMT2ACYP1A2GAA
SCHEMBL3101104 0.73 L3MBTL1 (0.53) L3MBTL1POLBKMT2ACYP1A2GAA
SCHEMBL9362311 0.73 CYP1A2 (0.45) L3MBTL1POLBKMT2ACYP1A2GAA
Succinic Acid Diethyl Ester SCHEMBL22780 0.73 GAA (0.67) L3MBTL1POLBCYP1A2GAAMGAM
Succinic Acid Diethyl Ester SCHEMBL27768067 0.73 GAA (0.67) L3MBTL1POLBCYP1A2GAAMGAM
SCHEMBL6117754 0.73 L3MBTL1 (0.45) L3MBTL1POLBKMT2ACYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4351954-A INSECTICIDES, HERBICIDES, FUNGICIDE, ENZYME INHIBITORS AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1982-09-28 US disclosed