Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185565 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL5881155 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL4634658 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL3162055 | 0.72 | TTR (0.37) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5681297 | 0.71 | CA1 (0.39) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6018014 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL297442 | 0.71 | GRIN2D (0.44) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18698310 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL6139486 | 0.70 | ALDH1A1 (0.42) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1019709 | 0.70 | MAPK1 (0.45) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363333-A | NITRIC OXIDE FILTER COMPRISING NITROSO COMPOUND ADSORBED ON ACTIVATED CARBON | BRITISH-AMERICAN TOBACCO COMPANY LIMITED (GB) | 1982-12-14 | — | — | US | disclosed |