Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.60 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320713 | 0.88 | PPARA (0.72) | PPARAPPARGACE | |
| SCHEMBL9161282 | 0.87 | ITGB3 (0.75) | PPARGITGB3ITGA2BACEMME | |
| SCHEMBL14338208 | 0.87 | ITGB3 (0.75) | PPARGITGB3ITGA2BACEMME | |
| SCHEMBL27703721 | 0.87 | ITGB3 (0.75) | PPARGITGB3ITGA2BACEMME | |
| SCHEMBL1023326 | 0.87 | ITGB3 (0.75) | PPARGITGB3ITGA2BACEMME | |
| SCHEMBL5396458 | 0.85 | ITGB3 (0.71) | PPARGITGB3ITGA2BACEMME | |
| SCHEMBL19170415 | 0.85 | ITGB3 (0.71) | PPARGITGB3ITGA2BACEMME | |
| SCHEMBL5401472 | 0.85 | ITGB3 (0.71) | PPARGITGB3ITGA2BACEMME | |
| SCHEMBL7318941 | 0.84 | PPARA (0.66) | PPARAPPARGACE | |
| SCHEMBL7318936 | 0.83 | PPARA (0.64) | PPARAPPARGMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350628-A | OXIDATIVE DEHYDROGENATION WITH A BENZOQUINONE | RESEARCH CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |
| US-4283328-A | TREATING AN N-BLOCKED AMINO ACID RESIDUE WITH A TETRAMETHYL GUANIDINIUM SALT OF A PEPTIDE CHAIN | RESEARCH CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4261884-A | DESIRABLE BIOLOGICAL PROPERTIES AND STABILITY TO ENZYME CLEAVAGE | RESEARCH CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |