SCHEMBL11240352

SCHEMBL11240352

ClCc1c(Cl)c(Cl)cc(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.50
HSD17B10 Q99714 6/20 0.50
TSHR P16473 6/20 0.50
CYP3A4 P08684 4/20 0.50
MAPK1 P28482 3/20 0.50
HSP90AA1 P07900 2/20 0.50
HIF1A Q16665 2/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
USP2 O75604 1/20 0.50
EGFR P00533 1/20 0.50
LMNA P02545 1/20 0.50
ESR1 P03372 1/20 0.50
ERBB2 P04626 1/20 0.50
CYP1A2 P05177 1/20 0.50
LCK P06239 1/20 0.50
FYN P06241 1/20 0.50
PGR P06401 1/20 0.50
POLB P06746 1/20 0.50
HTR1A P08908 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699419 0.82 CYP3A4 (0.53) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL9861621 0.80 HPGD (0.40) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL9861565 0.78 CYP3A4 (0.39) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL4842709 0.75
SCHEMBL10600544 0.73 CYP3A4 (0.38) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL6441243 0.73 HPGD (0.54) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL14143885 0.73 HPGD (0.48) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL7405800 0.72
SCHEMBL2810141 0.69
SCHEMBL27545982 0.69 HPGD (0.44) HPGDHSD17B10TSHRCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111620760-B Method for preparing 2,3,5, 6-tetrachlorobenzonitrile 中南民族大学 2022-05-24 CN claimed
CN-111620760-A Method for preparing 2,3,5, 6-tetrachlorobenzonitrile, special catalyst and preparation method 中南民族大学 2020-09-04 CN claimed
CN-100486944-C Novel method for preparing 1-hexene in presence of ethylene oligomerization catalyst system PETROCHINA CO LTD (CN) 2009-05-13 CN claimed
CN-1128776-C Catalyst for preparing 1-hexene from ethene by oligomerization and its application RES INST OF DAQING PETROCHEMIC (CN) 2003-11-26 CN claimed
CN-1294109-A Catalyst for preparing 1-hexene from ethene by oligomerization and its application RES INST OPF DAQING PETRO CHEM (CN) 2001-05-09 CN claimed
CN-111620760-B Method for preparing 2,3,5, 6-tetrachlorobenzonitrile 中南民族大学 2022-05-24 CN disclosed
CN-111620760-B Method for preparing 2,3,5, 6-tetrachlorobenzonitrile 中南民族大学 2022-05-24 CN disclosed
WO-2021067943-A1 PIEZO1 AGONISTS FOR THE PROMOTION OF BONE FORMATION BIOVENTURES, LLC (US) 2021-04-08 WO disclosed
CN-111620760-A Method for preparing 2,3,5, 6-tetrachlorobenzonitrile, special catalyst and preparation method 中南民族大学 2020-09-04 CN disclosed
CN-111620760-A Method for preparing 2,3,5, 6-tetrachlorobenzonitrile, special catalyst and preparation method 中南民族大学 2020-09-04 CN disclosed
CN-100486944-C Novel method for preparing 1-hexene in presence of ethylene oligomerization catalyst system PETROCHINA CO LTD (CN) 2009-05-13 CN disclosed
CN-1203034-C Method for preparing 1-hexene in presence of ethylene oligomerization catalyst system CHINA NAT PETROLEUM CORP (CN) 2005-05-25 CN disclosed
CN-1490291-A Method for preparing 1-hexene in presence of ethylene oligomerization catalyst system 中国石油天然气股份有限公司 2004-04-21 CN disclosed
CN-1490290-A Novel method for preparing 1-hexene in presence of ethylene oligomerization catalyst system 中国石油天然气股份有限公司 2004-04-21 CN disclosed
CN-1128776-C Catalyst for preparing 1-hexene from ethene by oligomerization and its application RES INST OF DAQING PETROCHEMIC (CN) 2003-11-26 CN disclosed
CN-1294109-A Catalyst for preparing 1-hexene from ethene by oligomerization and its application RES INST OPF DAQING PETRO CHEM (CN) 2001-05-09 CN disclosed
US-4318821-A Polymeric compositions ALBRIGHT & WILSON LIMITED (GB) 1982-03-09 US disclosed