SCHEMBL9861565

SCHEMBL9861565

ClCc1c(Cl)c(Cl)cc(C(Cl)Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
USP2 O75604 1/20 0.39
EGFR P00533 1/20 0.39
LMNA P02545 1/20 0.39
ESR1 P03372 1/20 0.39
ERBB2 P04626 1/20 0.39
CYP1A2 P05177 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
PGR P06401 1/20 0.39
POLB P06746 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
HSPA1A P0DMV8 1/20 0.39
AR P10275 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240352 0.78 HPGD (0.50) CYP3A4MEN1NPC1USP2EGFR
SCHEMBL11698546 0.76 CYP3A4 (0.32) CYP3A4SIRT1
SCHEMBL9861621 0.76 HPGD (0.40) CYP3A4MEN1NPC1USP2EGFR
SCHEMBL9321423 0.74 CYP3A4 (0.53) CYP3A4MEN1NPC1USP2EGFR
SCHEMBL9623249 0.67 LMNA (0.33) CYP3A4LMNAESR1MAPK1HTT
SCHEMBL1539461 0.65 AKR1B1 (0.42) CYP3A4NPC1LMNACYP1A2PGR
SCHEMBL11699419 0.64 CYP3A4 (0.53) CYP3A4MEN1NPC1USP2EGFR
SCHEMBL4842709 0.63
SCHEMBL10600544 0.61 CYP3A4 (0.38) CYP3A4MEN1NPC1USP2EGFR
SCHEMBL7405800 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0336361-B1 SULFUR-CONTAINING ACRYL OLIGOMER COMPOSITION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-04-10 EP disclosed
EP-0336361-A1 Sulfur-containing acryl oligomer composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-10-11 EP disclosed