Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532277 | 0.86 | CYP4F2 (0.58) | CYP4F2CYP4A11SMN1; SMN2NAMPTCYP1A2 | |
| SCHEMBL5694488 | 0.85 | CYP4F2 (0.59) | CYP4F2CYP4A11SMN1; SMN2NAMPTCYP1A2 | |
| SCHEMBL2498217 | 0.84 | TOP2A (0.56) | CYP4F2CYP4A11SMN1; SMN2NAMPTCYP1A2 | |
| SCHEMBL11302752 | 0.81 | EPHX2 (0.48) | KDM4EMAPTALOX5HSD17B10 | |
| SCHEMBL10408667 | 0.81 | LIPG (0.47) | SMN1; SMN2CYP3A4CYP2D6CYP2C9LMNA | |
| SCHEMBL4557996 | 0.81 | LIPG (0.51) | SMN1; SMN2LMNA | |
| SCHEMBL10409294 | 0.81 | LIPG (0.51) | SMN1; SMN2LMNA | |
| SCHEMBL8530220 | 0.80 | CYP4F2 (0.56) | CYP4F2CYP4A11SMN1; SMN2NAMPTCYP1A2 | |
| SCHEMBL10408672 | 0.79 | LIPG (0.49) | ALOX5 | |
| SCHEMBL15641739 | 0.79 | HPGD (0.48) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |