Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236984 | 0.91 | KDM4E (0.72) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL11405680 | 0.90 | KDM4E (0.49) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL11230075 | 0.89 | CNR2 (0.56) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL11237089 | 0.87 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL11234391 | 0.86 | ALDH1A1 (0.44) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL5680266 | 0.84 | KDM4E (0.59) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL4179844 | 0.83 | KDM4E (0.58) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL4179852 | 0.83 | KDM4E (0.58) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL4903449 | 0.80 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL4906790 | 0.80 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012925-B1 | QUINOLON-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-10 | — | — | EP | claimed |
| US-4289777-A | Quinolonecarboxylic acid derivatives and pharmaceutical preparations thereof for treatment of an allergic disease of the respiratory tract | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | claimed |
| EP-0012925-A1 | Quinolon-carboxylic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | claimed |
| EP-0012925-B1 | QUINOLON-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-10 | — | — | EP | disclosed |
| US-4289777-A | Quinolonecarboxylic acid derivatives and pharmaceutical preparations thereof for treatment of an allergic disease of the respiratory tract | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |
| EP-0012925-A1 | Quinolon-carboxylic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | disclosed |