Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DPYD | Q12882 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239608 | 0.81 | TSHR (0.53) | ALDH1A1KMT2ALMNAKDM4EMEN1 | |
| SCHEMBL124965 | 0.80 | KMT2A (0.60) | ALDH1A1KMT2ALMNAKDM4EGAA | |
| SCHEMBL11238669 | 0.79 | TSHR (0.55) | ALDH1A1LMNAKDM4EL3MBTL1POLB | |
| SCHEMBL11246059 | 0.79 | TSHR (0.55) | ALDH1A1LMNAKDM4EL3MBTL1POLB | |
| Isoorotic Acid Methyl Ester SCHEMBL7487788 | 0.74 | GAA (0.53) | ALDH1A1KMT2ALMNAKDM4EGAA | |
| SCHEMBL19500815 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAKDM4EL3MBTL1 | |
| Isoorotic Acid Methyl Ester SCHEMBL11253390 | 0.73 | GAA (0.51) | ALDH1A1KMT2ALMNAKDM4EGAA | |
| SCHEMBL29029122 | 0.71 | KMT2A (0.44) | ALDH1A1KMT2ALMNAKDM4EGAA | |
| SCHEMBL6524027 | 0.71 | GAA (0.50) | ALDH1A1KMT2ALMNAGAAMAPT | |
| SCHEMBL7024659 | 0.71 | KDM4E (0.38) | ALDH1A1LMNAKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |