Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815158 | 1.00 | TDP1 (0.54) | TDP1TSHRHSD17B10THRBALDH1A1 | |
| SCHEMBL11252889 | 1.00 | TDP1 (0.54) | TDP1TSHRHSD17B10THRBALDH1A1 | |
| SCHEMBL4063408 | 0.95 | TDP1 (0.50) | TDP1TSHRHSD17B10THRBALDH1A1 | |
| SCHEMBL503413 | 0.91 | TDP1 (0.44) | TDP1TSHRTHRBALDH1A1 | |
| SCHEMBL11111869 | 0.91 | TDP1 (0.44) | TDP1TSHRTHRBALDH1A1 | |
| SCHEMBL887703 | 0.91 | TDP1 (0.44) | TDP1TSHRTHRBALDH1A1 | |
| SCHEMBL4819070 | 0.89 | TSHR (0.49) | TDP1TSHR | |
| SCHEMBL9173131 | 0.88 | TSHR (0.47) | TDP1TSHRTHRBALDH1A1 | |
| SCHEMBL5450809 | 0.88 | TSHR (0.51) | TDP1TSHR | |
| SCHEMBL5449767 | 0.88 | TSHR (0.51) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310397-A | SUSTAINED RELEASE; PREPARED BY IRRADIATION POLYMERIZATION | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1982-01-12 | — | — | US | disclosed |