SCHEMBL1124069

SCHEMBL1124069

CN(C)c1ccc(/C=C/C(=O)O)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.75
MAPT P10636 3/20 0.62
NPC1 O15118 2/20 0.62
RAB9A P51151 2/20 0.62
KMT2A Q03164 2/20 0.62
CASP3 P42574 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
CYP1B1 Q16678 1/20 0.62
SENP8 Q96LD8 1/20 0.62
SENP7 Q9BQF6 1/20 0.62
SENP6 Q9GZR1 1/20 0.62
CRHBP P24387 1/20 0.60
CRHR2 Q13324 1/20 0.60
TLR9 Q9NR96 1/20 0.60
HCAR2 Q8TDS4 2/20 0.59
RELA Q04206 1/20 0.59
CA12 O43570 1/20 0.59
AKR1B10 O60218 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381477 1.00 HSD17B3 (0.75) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL3297165 0.94 HSD17B3 (0.68) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL3297156 0.94 HSD17B3 (0.68) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL560170 0.87 HDAC3 (0.71) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL560171 0.87 HDAC3 (0.71) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL3050207 0.86 HSD17B3 (1.00) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL814396 0.86 HSD17B3 (1.00) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL814395 0.86 HSD17B3 (1.00) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL18692411 0.85 HSD17B3 (0.70) HSD17B3MAPTNPC1RAB9AKMT2A
SCHEMBL18692409 0.85 HSD17B3 (0.70) HSD17B3MAPTNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574724-A Preparation method of fluorescent dye with high fluorescence quantum yield for diagnosis 广东普洛凯生物科技有限公司 2026-02-27 CN claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-20220259490-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2022-08-18 US claimed
WO-2020252075-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-12-17 WO claimed
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-01-28 US claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2017-12-21 US claimed
US-20170273323-A1 PRESERVATION OF MEAT PRODUCTS PURAC BIOCHEM B.V. (NL) 2017-09-28 US claimed
US-20100226823-A1 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2010-09-09 US claimed
EP-2226192-A1 Drying substances, preparation and use thereof Oridion Medical 1987 Ltd. (IL) 2010-09-08 EP claimed
US-7604746-B2 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2009-10-20 US claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
US-20030096394-A1 Laccase activity enhancers CODEXIS, INC. 2003-05-22 US claimed
WO-2003023043-A1 LACCASE ACTIVITY ENHANCERS CODEXIS INC. (US) 2003-03-20 WO claimed
US-5830999-A CARBOXYLIC LIGANDS, HEXAMERS REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-11-03 US claimed
US-4592906-A Ester of p-dimethylaminocinnamic acid GRAESSER LABORATORIES, LTD. (GB) 1986-06-03 US claimed
EP-0153089-A1 Ultra-violet absorbing compounds and compositions containing said compounds GRAESSER LABORATORIES LIMITED (GB) 1985-08-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same CA6, CA13, EPCAM HSD17B3 1732/4885MAPT 2354/4885NPC1 93/4885
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS HSD17B3 3807/4885MAPT 2153/4885NPC1 3543/4885
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME CA6, CA13, EPCAM HSD17B3 1732/4885MAPT 2354/4885NPC1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.