CA6

Carbonic anhydrase 6 · P23280 · CA6 on Sugi Atlas →

196,910 patent compounds predicted against CA6, 129,873 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Benzthiazide (SCHEMBL26257)	0.42	9/20
Mafenide (SCHEMBL41627)	0.77	7/20
Coumarin (SCHEMBL6252)	1.00	6/20
SCHEMBL19880	0.55	6/20
SCHEMBL16810	0.42	6/20
Benzthiazide (SCHEMBL26258)	0.42	6/20
Benzenesulfonamide (SCHEMBL729)	1.00	5/20
Sulfanilamide (SCHEMBL740)	1.00	5/20
Spermine (SCHEMBL14965)	1.00	5/20
Trientine (SCHEMBL15439)	1.00	5/20
Spermidine (SCHEMBL15618)	1.00	5/20
SCHEMBL15797	1.00	5/20
SCHEMBL26707	1.00	5/20
SCHEMBL28170	1.00	5/20
Mafenide (SCHEMBL41628)	1.00	5/20
SCHEMBL20976	0.86	5/20
SCHEMBL26667	0.85	5/20
Acetic Acid (SCHEMBL18288)	0.59	5/20
SCHEMBL15782	0.50	5/20
SCHEMBL22020	0.50	5/20

Clinical trials — most relevant to CA6 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary Artery Ectasia	PHASE4	RECRUITING
Vitamin D Dose-Response Study to Establish Dietary Requirements in Infants	PHASE2	COMPLETED
EF5 Compared With Other Methods of Detecting Oxygen Levels in Tumor Cells of Patients With Head and Neck Cancer	PHASE2	COMPLETED
Evaluation of Tumour Growth and Oncological Treatment in Patients With CRLM Using Zebra Fish Embryo Model	PHASE1/PHASE2	UNKNOWN
Phase I Trial of CArbonic Anhydrase Inhibition in Combination With Radiochemotherapy or Radioimmunotherapy in Small Cell Lung Carcinoma	PHASE1	RECRUITING
Biweekly SOLAR, as First-line C/T in Pts With Gastric, Pancreatic and Biliary Cancers	PHASE1	COMPLETED
Dosimetry, Safety, and Efficacy Study of [177Lu]Lu-XT771 in Patients With Recurrent Glioblastoma	EARLY_PHASE1	RECRUITING
The Etiology and Progression of Brain Tumors	nan	COMPLETED
Incidence of Renal Tubular Acidosis in Nephrology Unit in Assiut University Childern Hospital	nan	UNKNOWN
Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized Kidney Cancer	nan	WITHDRAWN
Study on the Diagnostic Value of Novel PET Molecular Imaging for Renal Cell Carcinoma	nan	RECRUITING
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Radiomics: a Study of Outcome in Lung Cancer	nan	COMPLETED
Role of Geminin and Mcm-2 in Prognosis of Renal Cell Carcinoma	nan	UNKNOWN
A Longitudinal Study to Analyse the Correlation Between CAI and Bilirubin	nan	UNKNOWN
Multicenter Study of 18F-Labeled NY104 for PET/CT Imaging in Renal Cell Carcinoma	nan	RECRUITING
Selecting Hypoxic Tumours for Treatment Modification	nan	RECRUITING
Calciotropic Effects After HCG Stimulation Test	nan	COMPLETED
Assessing Bone Calcium Content in Children With Kidney Disease Treated With Two Different Medicines	nan	UNKNOWN
Improving Safety in Pediatric Thyroidectomy by PTH Measurements	nan	COMPLETED
Long Term Prognostic of Neonatal Hypoxic Ischemic Encephalopathy With Hypothermia Treatment	nan	UNKNOWN
Oxalate and Citrate in Humans - Response to Citrate	nan	RECRUITING
Biomarker for Hereditary AngioEdema Disease	nan	COMPLETED
The Influence of Secretin Stimulated Pancreatic Secretion on ctDNA Expression in Patients With Pancreatic Ductal Adenocarcinoma: The Role of Biomarkers in Determining the Prognosis of Pancreatic Ductal Adenocarcinoma	nan	NOT_YET_RECRUITING
Risk Factors for the Development of Celiac Disease in Genetically Predisposed Children	nan	UNKNOWN
Bone Density and Vascular Calcifications Evolution After Renal Transplant	nan	RECRUITING
Implication of Long Non-coding RNA CCDC144NL-AS1/Micro RNA-143-3p Axis Expression Level as Novel Signature in Colorectal Cancer	nan	COMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED
Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors	nan	RECRUITING
Cardiovascular Effects of Empagliflozine	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a CA6 binder may also engage these)

Protein	Name	Similarity
Q865C0	—	1.000	Q865C0 →
P18915	—	1.000	P18915 →
P08060	—	0.995	P08060 →
Q8CI85	—	0.986	Q8CI85 →
Q5R4U0	—	0.986	Q5R4U0 →
Q9MZ30	—	0.985	Q9MZ30 →
A0JN41	—	0.984	A0JN41 →
F4HUC4	—	0.982	F4HUC4 →
Q9N085	—	0.981	Q9N085 →
Q18932	—	0.981	Q18932 →
Q9NS85	—	0.980	Q9NS85 →
Q64444	—	0.978	Q64444 →
CA12	Carbonic anhydrase 12	0.978	landscape →
F4IHR4	—	0.977	F4IHR4 →
Q10462	—	0.976	Q10462 →
O04846	—	0.976	O04846 →
P61215	—	0.976	P61215 →
P18761	—	0.975	P18761 →
P0DO50	—	0.974	P0DO50 →
Q9FYE3	—	0.971	Q9FYE3 →
F4JIK2	—	0.970	F4JIK2 →
P48284	—	0.970	P48284 →
Q8L817	—	0.969	Q8L817 →
P28651	—	0.968	P28651 →
Q6UVY6	—	0.967	Q6UVY6 →
Q9CXI3	—	0.967	Q9CXI3 →
Q75N35	—	0.967	Q75N35 →
P35219	—	0.966	P35219 →
Q95323	—	0.966	Q95323 →
Q5PPN4	—	0.966	Q5PPN4 →