Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.44 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243340 | 1.00 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1S1PR1HPGD | |
| SCHEMBL11244302 | 1.00 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1S1PR1HPGD | |
| SCHEMBL11228905 | 1.00 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1S1PR1HPGD | |
| SCHEMBL11236131 | 1.00 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1S1PR1HPGD | |
| SCHEMBL11226805 | 1.00 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1S1PR1HPGD | |
| SCHEMBL11240378 | 0.93 | CYP4Z1 (0.52) | CYP4F2CYP4A11CYP4Z1S1PR1HPGD | |
| SCHEMBL11245397 | 0.90 | SCN5A (0.49) | CYP4F2CYP4A11S1PR1HPGDABCB11 | |
| SCHEMBL11241265 | 0.90 | SCN5A (0.49) | CYP4F2CYP4A11S1PR1HPGDABCB11 | |
| SCHEMBL11235318 | 0.90 | SCN5A (0.49) | CYP4F2CYP4A11S1PR1HPGDABCB11 | |
| SCHEMBL11586841 | 0.89 | S1PR1 (0.51) | CYP4F2CYP4A11CYP4Z1S1PR1CYP4F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |