Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 3/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240789 | 1.00 | S1PR3 (0.44) | S1PR3PLK1ZDHHC2APPEGFR | |
| SCHEMBL11240150 | 0.85 | ZDHHC2 (0.48) | S1PR3PLK1ZDHHC2APPEGFR | |
| SCHEMBL11240154 | 0.85 | ZDHHC2 (0.48) | S1PR3PLK1ZDHHC2APPEGFR | |
| SCHEMBL11468900 | 0.84 | S1PR3 (0.49) | S1PR3PLK1HCAR3MEN1KMT2A | |
| SCHEMBL11229500 | 0.82 | ZDHHC2 (0.60) | ZDHHC2EGFRKMT2ATUBB4ATUBB | |
| SCHEMBL11229503 | 0.82 | ZDHHC2 (0.60) | ZDHHC2EGFRKMT2ATUBB4ATUBB | |
| SCHEMBL11229891 | 0.76 | CA12 (0.57) | PLK1APPEGFR | |
| SCHEMBL11229892 | 0.76 | CA12 (0.57) | PLK1APPEGFR | |
| SCHEMBL11240157 | 0.75 | EGFR (0.56) | PLK1APPEGFRTUBB4ATUBB | |
| SCHEMBL11240642 | 0.75 | EGFR (0.56) | PLK1APPEGFRTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |