Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240154 | 1.00 | ZDHHC2 (0.48) | ZDHHC2KMT2ATP53TSHRAPP | |
| SCHEMBL11229500 | 0.90 | ZDHHC2 (0.60) | ZDHHC2KMT2AEGFRTUBB4ATUBB | |
| SCHEMBL11229503 | 0.90 | ZDHHC2 (0.60) | ZDHHC2KMT2AEGFRTUBB4ATUBB | |
| SCHEMBL11240789 | 0.85 | S1PR3 (0.44) | ZDHHC2KMT2AAPPPLK1HTT | |
| SCHEMBL11240786 | 0.85 | S1PR3 (0.44) | ZDHHC2KMT2AAPPPLK1HTT | |
| SCHEMBL11376686 | 0.83 | MGLL (0.55) | TP53TSHRPLK1PLA2G4BKDM4E | |
| SCHEMBL11668161 | 0.82 | TP53 (0.68) | TP53TSHRPLA2G4BRARB | |
| SCHEMBL11280086 | 0.81 | HCAR3 (0.59) | KMT2ATP53TSHRPLK1PLA2G4B | |
| SCHEMBL2309354 | 0.81 | HCAR3 (0.59) | KMT2ATP53TSHRPLK1PLA2G4B | |
| SCHEMBL22398313 | 0.81 | HCAR3 (0.59) | KMT2ATP53TSHRPLK1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |