Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18209405 | 0.84 | CA12 (0.53) | KDM4EMAPK1CA12CA1CA2 | |
| SCHEMBL1515872 | 0.79 | CA12 (0.62) | KDM4EHSD17B10MAPK1CA12CA1 | |
| SCHEMBL29022766 | 0.77 | KDM4E (0.51) | KDM4EHSD17B10MAPK1CA12CA1 | |
| SCHEMBL23706692 | 0.76 | CA12 (0.51) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL1975607 | 0.75 | GABRA1 (0.53) | KDM4EPTPN1CYP3A4KMT2AALDH1A1 | |
| SCHEMBL16302043 | 0.75 | TSHR (0.61) | KDM4EHSD17B10MAPK1CA12CA1 | |
| SCHEMBL18311390 | 0.74 | CA12 (0.53) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL14468249 | 0.74 | TSHR (0.52) | KDM4EHSD17B10MAPK1CA12CA1 | |
| SCHEMBL28654509 | 0.74 | CA12 (0.56) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL4251896 | 0.74 | TSHR (0.62) | KDM4EHSD17B10MAPK1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57115458-A | — | — | None | — | — | JP | disclosed |
| JP-S57115458-A | STABILIZED SYNTHETIC RESIN COMPOSITION | SUMITOMO CHEM CO LTD | 1982-07-17 | — | — | JP | disclosed |