Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MGMT | P16455 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151311 | 0.85 | CYP19A1 (0.60) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL30354908 | 0.85 | CYP19A1 (0.60) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL2191697 | 0.84 | MAPT (0.65) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL29433280 | 0.84 | MAPT (0.65) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL29151228 | 0.84 | SMN1; SMN2 (0.65) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL30354847 | 0.84 | SMN1; SMN2 (0.65) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL11249195 | 0.82 | MAPT (0.49) | CYP19A1MAPTRAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL30638121 | 0.81 | KMT2A (0.54) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL2702769 | 0.81 | KMT2A (0.54) | CYP19A1CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL4029719 | 0.80 | KMT2A (0.56) | MAPTRAB9ANPSR1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102766068-A | Halogenated salicyloyl arylamine compounds as well as preparation method and application thereof | ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE | 2012-11-07 | — | — | CN | disclosed |
| US-4332944-A | Compositions and use | ZOECON CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |