SCHEMBL11241545

CC(=O)O[C@@H]1CC[C@@]2(C)[C@H](C1)[C@@H](OC(C)=O)C[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)CCC=O)CC[C@@H]12

nearest known ligand 0.57

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	USP2	O75604	1/20	0.57

▸	VDR	P11473	1/20	0.57

▸	CDC25A	P30304	2/20	0.47

▸	GPBAR1	Q8TDU6	4/20	0.46

▸	MAPT	P10636	1/20	0.46

▸	THRB	P10828	1/20	0.46

▸	ST6GAL1	P15907	1/20	0.45

▸	DHCR24	Q15392	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11326505	0.87	VDR (0.74)	USP2VDRGPBAR1MAPTTHRB
SCHEMBL12903058	0.87	VDR (0.74)	USP2VDRGPBAR1MAPTTHRB
SCHEMBL11291812	0.86	VDR (0.62)	USP2VDRGPBAR1MAPTTHRB
SCHEMBL11520515	0.86	USP2 (0.57)	USP2VDRCDC25AGPBAR1MAPT
SCHEMBL5337856	0.86	VDR (0.62)	USP2VDRGPBAR1MAPTTHRB
SCHEMBL11295242	0.86	USP2 (0.57)	USP2VDRCDC25AGPBAR1MAPT
SCHEMBL11293736	0.85	VDR (0.60)	USP2VDRGPBAR1MAPTTHRB
SCHEMBL11234455	0.84	USP2 (0.45)	USP2VDRCDC25AGPBAR1MAPT
SCHEMBL11235985	0.82	P2RY12 (0.42)	USP2VDRCDC25AGPBAR1MAPT
SCHEMBL12903060	0.82	USP2 (0.48)	USP2VDRGPBAR1MAPTST6GAL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4354972-A	Synthesis of steroids	KAISER EMIL T	1982-10-19	—	—	US	disclosed