VDR

Vitamin D3 receptor · P11473 · VDR on Sugi Atlas →

49,945 patent compounds predicted against VDR, 32,773 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Calcipotriene (SCHEMBL297984)	0.67	14/20
Maxacalcitol (SCHEMBL2745)	1.00	13/20
Calcipotriene (SCHEMBL2853)	1.00	13/20
Calcipotriene (SCHEMBL2854)	1.00	13/20
Seocalcitol (SCHEMBL3790)	1.00	13/20
Seocalcitol (SCHEMBL3791)	1.00	13/20
Maxacalcitol (SCHEMBL342279)	1.00	13/20
Calcipotriene (SCHEMBL465450)	0.98	13/20
SCHEMBL764692	0.81	13/20
Paricalcitol (SCHEMBL3655)	0.68	13/20
SCHEMBL817092	0.51	13/20
SCHEMBL818214	0.51	13/20
Ercalcitriol (SCHEMBL264875)	0.80	12/20
Ercalcitriol (SCHEMBL264876)	0.80	12/20
Ercalcitriol (SCHEMBL301082)	0.80	12/20
Ercalcitriol (SCHEMBL301083)	0.80	12/20
Ercalcitriol (SCHEMBL465997)	0.80	12/20
SCHEMBL296082	0.76	12/20
SCHEMBL67842	0.64	12/20
SCHEMBL67867	0.64	12/20

Clinical trials — most relevant to VDR by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Investigating the Effects of Hydroxyvitamin D3 on Multiple Sclerosis	PHASE4	UNKNOWN
Efficacy of Fractional CO2 Laser as a Mono- or Adjuvant Therapy for Alopecia Areata	PHASE4	UNKNOWN
The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff	PHASE4	COMPLETED
Can Vitamin D3 Supplementation Affect Treatment Outcomes in Patients With Depression	PHASE4	UNKNOWN
Vitamin-D Receptor Activation (VDRA) in Chronic Kidney Disease	PHASE2/PHASE3	COMPLETED
Kabul Vitamin D Supplementation Trial	PHASE3	UNKNOWN
Vitamin D/Calcium Polyp Prevention Study	PHASE2/PHASE3	COMPLETED
Vitamin D Supplementation in HIV-infected Youth	PHASE2	COMPLETED
Vitamin D Supplementation in Cirrhotic Patients	PHASE2	COMPLETED
Effects of Vitamin D Supplementation on Muscle Protein Synthesis	PHASE2	COMPLETED
The Effect of a High-dose Oral Vitamin D3 Bolus on Serum 25(OH)D3 and Vitamin D Receptor Target Gene Expression	PHASE1	COMPLETED
Study of Vitamin D for Premenopausal Women at High Risk for Breast Cancer	PHASE1	COMPLETED
Use of Vitamin D as An Adjuvant Treatment in Children With Chronic Idiopathic Thrombocytopenic Purpura	EARLY_PHASE1	UNKNOWN
Prognostic Value of Vitamin D Levels in Egyptian Females With Breast Cancer	nan	UNKNOWN
The Impact of Selective Vitamin D Receptor Activation on Clinical Outcomes in Septic Patients	nan	NOT_YET_RECRUITING
Immunolocalization of 1,25,Dihydroxyvitamin D3 in Aggressive Periodontitis Patients	nan	COMPLETED
Ischemic Preconditioning - Perspectives of Use Vivio/in Vitro Studies	nan	ENROLLING_BY_INVITATION
Assessment of the Different Etiological and Susceptibility Markers in Patients With Pancreatitis: Investigating IG4, Cytomegalovirus, Coxsackie- Virus, Genetic Polymorphism of Vitamin D Receptor Gene	nan	UNKNOWN
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages	nan	COMPLETED
Assessing the Effects of Alfacalcidol Intake on Expression of Involed Gene in Metabolism in Obese Subjects	nan	UNKNOWN
The Role of Programmed Death Ligand -1 (Pdl-1) in Lung Cancer	nan	COMPLETED
Is There Association Between Vitamin D Levels And Insulin Resistance In Polycystic Ovary Syndrome?	nan	UNKNOWN
Calcifediol in the Treatment of SARS-CoV-2 Disease (COVID-19).	nan	COMPLETED
S0812 High Dose Cholecalciferol in Premenopausal Women at High-Risk for Breast Cancer	nan	COMPLETED
Vitamin D Levels in Liver Transplantation Recipients Prospective Observational Study	nan	COMPLETED
Regulation of Vitamin D Receptor (VDR),Calcium Sensing Receptor (CaSR), Cyclin D1,Ki67 and Proliferating Cell Nuclear Antigen (PCNA) in Primary Hyperparathyroidism	nan	UNKNOWN
Replacement of Vitamin D in Patients With Active Tuberculosis	nan	COMPLETED
The Prevalence of Vitamin D Deficiency in Patients With Alzheimer's Disease	nan	COMPLETED
Co-stimulatory Markers and Vitamin D Status in Anti-PD1 Treated Melanoma Patients	nan	COMPLETED
Evaluation of Vitamin D in Women With PCOS and Sexual Dysfunction	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a VDR binder may also engage these)

Protein	Name	Similarity
A3RGC1	—	1.000	A3RGC1 →
Q28037	—	1.000	Q28037 →
P13053	—	1.000	P13053 →
P48281	—	1.000	P48281 →
Q95MH5	—	1.000	Q95MH5 →
P49701	—	1.000	P49701 →
Q1L673	—	1.000	Q1L673 →
O42392	—	1.000	O42392 →
Q9W785	—	1.000	Q9W785 →
F1QLY4	—	1.000	F1QLY4 →
Q9W6N4	—	1.000	Q9W6N4 →
Q9PTN2	—	1.000	Q9PTN2 →
O57606	—	1.000	O57606 →
Q28570	—	1.000	Q28570 →
P18119	—	1.000	P18119 →
O13124	—	1.000	O13124 →
O42450	—	1.000	O42450 →
Q91241	—	1.000	Q91241 →
THRB	Thyroid hormone receptor beta	0.999	landscape →
Q91279	—	0.998	Q91279 →
P51448	—	0.998	P51448 →
Q91242	—	0.997	Q91242 →
Q02777	—	0.997	Q02777 →
Q9YGL3	—	0.997	Q9YGL3 →
Q90382	—	0.997	Q90382 →
P18117	—	0.997	P18117 →
P37242	—	0.997	P37242 →
P49882	—	0.996	P49882 →
P45446	—	0.996	P45446 →
P28700	—	0.996	P28700 →